Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

DR1058 Anti-SOCS3 Mouse mAb (1E4)

This Anti-SOCS3 Mouse mAb (1E4) is validated for use in ELISA, Paraffin Sections for the detection of SOCS3.

Anti-SOCS3 Mouse mAb (1E4) MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Anti-Suppressor Cytokine Signaling 3

DR1058
  
Purchase on Sigma-Aldrich

Áttekintés

Replacement Information

Kulcsspecifikációk táblázata

Species ReactivityHostAntibody Type
HMMonoclonal Antibody
Description
OverviewRecognizes the SOCS3 protein in human colon tissue.
Catalogue NumberDR1058
Brand Family Calbiochem®
SynonymsAnti-Suppressor Cytokine Signaling 3
Application Data
Detection of human SOCS3 by staining paraffin sections. Sample: Formalin-fixed, paraffin embedded human colon tissue. Primary antibody: Anti-SOCS3 Mouse mAb (1E4) (Cat. No. DR1058) (1.5 µg/ml). Detection: colorimetric (DAB).
References
Product Information
Formliquid
FormulationIn PBS, pH 7.2.
Positive controlHuman colon tissue
PreservativeNone
Applications
Key Applications Enzyme-Linked Immunosorbent Assay
Paraffin Sections
Application NotesELISA (see comments)
Paraffin Sections (1.5 µg/ml)
Application CommentsVariables associated with assay conditions will dictate the proper working dilution.
Biological Information
ImmunogenFull-length, recombinant human SOCS3 (aa 1-226), expressed as a GST fusion protein
ImmunogenNA
Clone1E4
HostMouse
IsotypeIgG2b
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Blue Ice Only
Toxicity Regulatory Review
Storage -20°C
Avoid freeze/thaw Avoid freeze/thaw
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalógusszám GTIN
DR1058 0

Documentation

Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision04-November-2010 RFH
SynonymsAnti-Suppressor Cytokine Signaling 3
ApplicationELISA (see comments)
Paraffin Sections (1.5 µg/ml)
Application Data
Detection of human SOCS3 by staining paraffin sections. Sample: Formalin-fixed, paraffin embedded human colon tissue. Primary antibody: Anti-SOCS3 Mouse mAb (1E4) (Cat. No. DR1058) (1.5 µg/ml). Detection: colorimetric (DAB).
DescriptionPurified mouse monoclonal antibody. Recognizes the SOCS3 protein.
BackgroundThis protein is a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. This protein can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development.
HostMouse
Immunogen speciesNA
ImmunogenFull-length, recombinant human SOCS3 (aa 1-226), expressed as a GST fusion protein
Clone1E4
IsotypeIgG2b
Specieshuman
Positive controlHuman colon tissue
Formliquid
FormulationIn PBS, pH 7.2.
PreservativeNone
CommentsVariables associated with assay conditions will dictate the proper working dilution.
Storage Avoid freeze/thaw
-20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
Toxicity Regulatory Review