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ABS521 Anti-RSK4 Antibody

ABS521
100 µg  
Purchase on Sigma-Aldrich

Különleges ajánlatok

Áttekintés

Replacement Information

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Kulcsspecifikációk táblázata

Species ReactivityKey ApplicationsHostFormatAntibody Type
RWB, IPRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABS521
Replaces04-1132
DescriptionAnti-RSK4 Antibody
Alternate Names
  • Q9UK32
  • KS6A6_HUMAN
  • RPS6KA6
  • RSK4
  • Q9UK32
  • B2R854
  • Q6FHX2
  • Q8WX28
  • Q9H4S6
  • Ribosomal protein S6 kinase alpha-6
  • p90RSK6
Background InformationRSK1, RSK2, RSK3, and RSK4 (ribosomal protein S6 kinase, 90 kDa, polypeptide 1,2,3, and 4; S6K-alpha 1,2,3, and 4) are Ser/Thr kinases which are activated by MAP Kinases. Ribosomal S6-kinase 4 (RSK4) is thought to be mapped in the critical region that is commonly deleted in X-linked deafness type 3, mental retardation, and choroideremia. It may be involved in normal neuronal development. RSK4 is also thought to play a role in non-growth factor signaling and may also be important in tumor suppression.
References
Product Information
FormatAffinity Purified
PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationThis Anti-RSK4 Antibody is validated for use in Western Blotting and Immunoprecipitation for the detection of RSK4.
Key Applications
  • Western Blotting
  • Immunoprecipitation
Application NotesImmunoprecipitation analysis: 10 ug of Cat. No. ABS521, Anti-RSK4 was used to immunoprecipitate RSK4 in 0.5 mg PC12 or EGF treated PC12 cell lysate
Immunoprecipitation analysis: 5 ug of Cat. No. ABS521, Anti-RSK4 was used to immunoprecipitate RSK4 in 0.665mg of PC12 cell lysate. Uncharacterized bands may be detected at high antibody concentration or longer exposures
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to the C-terminus of Human RSK4.
EpitopeC-terminus
ConcentrationPlease refer to lot specific datasheet.
HostRabbit
Species Reactivity
  • Rat
Species Reactivity NoteRat. Predicted to react with Human, Bovine based on 100% sequence homology.
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • RPS6KA6
Purification MethodAntigen Affinity Purified
UniProt Number
Molecular Weight~83 kDa observed. Uncharacterized band(s) may appear in some lysates.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in rat PC12 cell lysate.

Western Blotting Analysis: 1 µg/mL of this antibody detected RSK4 in 10 µg of rat PC12 cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalógusszám GTIN
ABS521 04053252982163