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MABS1966-100UG Anti-PEG Antibody, clone 6.3

MABS1966-100UG
100 μg  
Purchase on Sigma-Aldrich

Áttekintés

Replacement Information
Description
Catalogue NumberMABS1966-100UG
DescriptionAnti-PEG Antibody, clone 6.3
Alternate Names
  • Polyethylene Glycol
Background InformationPolyethylene glycols (PEG) are non-toxic, uncharged, hydrophilic long chain polymers with a big exclusion volume in aqueous solution. The covalent attachment of PEG is commonly employed to modify proteins and drugs that can increase their bioavailability and reduce immunogenicity and proteolytic degradation. Clone 6.3 displays high affinity and binds the PEG backbone and can be employed as a detection antibody for the quantification of PEG. It binds to a smaller epitope of the PEG backbone when compared to other antibodies. Since it binds to a smaller PEG epitope (~750 Da), it is not compatible with detergents that contain an ethylene oxide backbone, such as Tween 20. Instead 0.05% CHAPS is a more suitable detergent when using this antibody.
References
Product Information
FormatPurified
PresentationPurified mouse monoclonal antibody IgG1 in PBS with 0.04% sodium azide.
Applications
ApplicationAnti-PEG, clone 6.3, Cat. No. MABS1966, is a mouse monoclonal antibody that detects PEG-conjugated proteins and it hs been tested for use in ELISA.
Key Applications
  • ELISA
Application NotesELISA Analysis: A representative lot detected PEG in ELISA applications (Tung, H.Y., et. al. (2015). Mol Cancer Ther. 14(6):1317-26).
Biological Information
ImmunogenPEG-conjugated to E.coli beta-glucuronidase.
Clone6.3
ConcentrationPlease refer to lot specific datasheet.
HostMouse
SpecificityClone 6.3 specifically detects proteins conjugated with polyethylene glycol (PEG).
IsotypeIgG1κ
Species Reactivity
  • All
Species Reactivity NoteAll.
Antibody TypeMonoclonal Antibody
Purification MethodProtein A purified
Molecular WeightN/A
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by ELISA in Immobilized PEG (10K-PEG, 3K-PEG, and 2K-mPEG).

ELISA Analysis: 5 µg/mL of Immobilized PEG (10K-PEG, 3K-PEG, and 2K-mPEG) were detected with this antibody.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 μg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalógusszám GTIN
MABS1966-100UG 04054839607684

Documentation

Anti-PEG Antibody, clone 6.3 MSDS

Title

Safety Data Sheet (SDS) 

Anti-PEG Antibody, clone 6.3 Certificates of Analysis

TitleLot Number
Anti-PEG, clone 6.3 - 3577441 3577441
Anti-PEG, clone 6.3 - 3605467 3605467
Anti-PEG, clone 6.3 - 3698554 3698554
Anti-PEG, clone 6.3 - 3831390 3831390
Anti-PEG, clone 6.3 - 4020577 4020577
Anti-PEG, clone 6.3 - 4045888 4045888
Anti-PEG, clone 6.3 - 4067249 4067249
Anti-PEG, clone 6.3 - 4085579 4085579
Anti-PEG, clone 6.3 - 4086382 4086382
Anti-PEG, clone 6.3 - 4151750 4151750