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MABE268 Anti-Musashi-1 Antibody, clone 7B11.1

MABE268
100 µg  
Purchase on Sigma-Aldrich

Különleges ajánlatok

Áttekintés

Replacement Information

Különleges ajánlatok

Kulcsspecifikációk táblázata

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, M, RWB, IHCMPurifiedMonoclonal Antibody
Description
Catalogue NumberMABE268
Replaces03-114; 04-1041
DescriptionAnti-Musashi-1 Antibody, clone 7B11.1
Alternate Names
  • RNA-binding protein Musashi homolog 1
Background InformationIn mammals, the Musashi family is important for cell fate determination, playing roles in maintenance of the stem-cell state, cellular differentiation, nuclear signaling and tumorigenesis. Musashi-1 (also known as Msi1), is selectivley expressed in neural progenitor cells, including neural stem cells. Outside the nervous system, Musashi-1 is a selective marker for intestinal stem or early lineage cells. Musashi-1 interacts with the Notch pathway during asymmetric cell division by binding the 3' UTR of Numb. Numb is prevented from repressing Notch signaling when Musashi-1 is present.
References
Product Information
FormatPurified
Control
  • Mouse E17 spinal cord tissue lysate.
PresentationPurified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationUse Anti-Musashi-1 Antibody, clone 7B11.1 (Mouse Monoclonal Antibody) validated in WB, IHC to detect Musashi-1 also known as RNA-binding protein Musashi homolog 1.
Key Applications
  • Western Blotting
  • Immunohistochemistry
Application NotesWestern Blot Analysis: A representative lot detected Musashi-1 in HEK293, NIH/3T3, and PC-12 cell lysate.

Immunohistochemistry Analysis: A 1:1,000 dilution of this antibody detected Musashi-1 in mouse cerebellum, normal mouse brain, and normal human pons tissue.
Biological Information
ImmunogenGST-tagged recombinant protein corresponding to human Musashi-1.
Clone7B11.1
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostMouse
IsotypeIgG2aκ
Species Reactivity
  • Human
  • Mouse
  • Rat
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • MSI1
Purification MethodProtein G Purified
UniProt Number
Molecular Weight~39 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blot in mouse E17 spinal cord tissue lysate.

Western Blot Analysis: 1 µg/mL of this antibody detected Musashi-1 in 10 µg of mouse E17 spinal cord tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalógusszám GTIN
MABE268 04053252440434

Documentation

Anti-Musashi-1 Antibody, clone 7B11.1 MSDS

Title

Safety Data Sheet (SDS) 

Anti-Musashi-1 Antibody, clone 7B11.1 Certificates of Analysis

TitleLot Number
Anti-Musashi-1, clone 7B11.1 2485876
Anti-Musashi-1, clone 7B11.1 - 2389951 2389951
Anti-Musashi-1, clone 7B11.1 - 2460979 2460979
Anti-Musashi-1, clone 7B11.1 - 2464645 2464645
Anti-Musashi-1, clone 7B11.1 - 3284330 3284330
Anti-Musashi-1, clone 7B11.1 - 3385845 3385845
Anti-Musashi-1, clone 7B11.1 - 3918063 3918063
Anti-Musashi-1, clone 7B11.1 - 4150407 4150407
Anti-Musashi-1, clone 7B11.1 - Q2017859 Q2017859
Anti-Musashi-1, clone 7B11.1 -2571254 2571254

Kapcsolódó termékek és alkalmazások

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Kategóriák

Life Science Research > Antibodies and Assays > Primary Antibodies