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ABT407 Anti-MYOZAP Antibody

Anti-MYOZAP Antibody detects level of MYOZAP & has been published & validated for use in MYOZAP.

Anti-MYOZAP Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Cell Structure Research Sub-Category: Cytoskeleton Gene Symbol: MYZAP, MYOZAP UniProt Number: P0CAP1
ABT407
100 µg  
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Kulcsspecifikációk táblázata

Species ReactivityKey ApplicationsHostFormatAntibody Type
RWBRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABT407
DescriptionAnti-MYOZAP Antibody
Alternate Names
  • Myocardial zonula adherens protein
  • GRINL1A upstream protein
  • Gup
Background InformationMyocardial zonula adherens protein, also known as GRINL1A upstream protein (Gup), and encoded by the gene name MYZAP or MYOZAP, is a 54 kDa highly conserved cardiac protein. It is strongly expressed in the heart and lung and is a novel component of intercalated disc. MYOZAP interacts with myosin phosphatase–RhoA interacting protein (MRIP) and acts as an activator of Rhodependent SRF signaling. Knockdown study in zebrafish results in cardiomyopathy with severe dysfunction. The MYOZAP gene is part of a complex transcript unit that includes the gene for glutamate receptor, ionotropic, Nmethyl D-aspartate-like 1A (GRINL1A). Transcription of this gene occurs at an upstream promoter, with two different groups of alternatively spliced variants: Gup for GRINL1A upstream transcripts and Gcom for GRINL1A combined transcripts.
References
Product Information
FormatAffinity Purified
PresentationPurified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-MYOZAP Antibody detects level of MYOZAP & has been published & validated for use in MYOZAP.
Key Applications
  • Western Blotting
Biological Information
ImmunogenKLH-conjugated synthetic peptide corresponding to the C-terminus of human MYOZAP.
EpitopeC-terminus
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
Species Reactivity
  • Rat
Antibody TypePolyclonal Antibody
Gene Symbol
  • MYZAP
  • MYOZAP
Purification MethodAntigen Affinity Purified
UniProt Number
Molecular Weight~54 kDa observed. Uncharacterized bands may be observed in some lysate(s). Uniprot describes 11 isoforms produced by alternative splicing ranging between ~44 kDa and ~54 kDa.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in rat kidney tissue lysate.

Western Blotting Analysis: 1 μg/mL of this antibody detected MYOZAP in rat kidney tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalógusszám GTIN
ABT407 04053252953071