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420293 Anti-IRS-2 (1122-1321) Rabbit pAb

420293
  
Purchase on Sigma-Aldrich

Áttekintés

Replacement Information

Kulcsspecifikációk táblázata

Host
Rb
Description
Overview

This product has been discontinued.



Please refer to our complete listing of IRS antibodies for possible alternatives.






Recognizes the ~180 kDa IRS-2 protein.
Catalogue Number420293
Brand Family Calbiochem®
SynonymsAnti-Insulin Receptor Substrate 2
References
ReferencesZhande, R., et al. 2002. Mol. Cell Biol. 22, 1016.
Qiao, L., et al. 1999. J. Biol. Chem. 274, 10625.
Sun, X.J., et al. 1999. Diabetes 48, 1359.
Product Information
FormLiquid
FormulationUndiluted serum.
PreservativeNone
Applications
Key Applications Immunoblotting (Western Blotting)
Immunoprecipitation
Application NotesImmunoblotting (1:500)
Immunoprecipitation (1:200)
Application CommentsDoes not cross-react with IRS-1. Variables associated with assay conditions will dictate the proper working dilution.
Biological Information
Immunogena recombinant protein containing amino acids 1122-1321 of mouse IRS-2 fused to GST
ImmunogenMouse
HostRabbit
IsotypeIgG
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Standard Handling
Storage -20°C
Avoid freeze/thaw Avoid freeze/thaw
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalógusszám GTIN
420293 0

Documentation

Anti-IRS-2 (1122-1321) Rabbit pAb Certificates of Analysis

TitleLot Number
420293

References

Hivatkozások áttekintése
Zhande, R., et al. 2002. Mol. Cell Biol. 22, 1016.
Qiao, L., et al. 1999. J. Biol. Chem. 274, 10625.
Sun, X.J., et al. 1999. Diabetes 48, 1359.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision12-October-2007 JSW
SynonymsAnti-Insulin Receptor Substrate 2
ApplicationImmunoblotting (1:500)
Immunoprecipitation (1:200)
DescriptionRabbit polyclonal antibody supplied as undiluted serum. Recognizes the ~180 kDa IRS-2 protein.
BackgroundUpon insulin stimulation, IRS proteins are phosphorylated by insulin receptor tyrosine kinase. Decreased levels of IRS proteins are associated with insulin resistance in humans. IRS-2 can serve as an alternative insulin substrate in IRS-1 deficient mice.
HostRabbit
Immunogen speciesMouse
Immunogena recombinant protein containing amino acids 1122-1321 of mouse IRS-2 fused to GST
IsotypeIgG
Specieshamster, human, mouse, rat
FormLiquid
FormulationUndiluted serum.
PreservativeNone
CommentsDoes not cross-react with IRS-1. Variables associated with assay conditions will dictate the proper working dilution.
Storage Avoid freeze/thaw
-20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
Toxicity Standard Handling
ReferencesZhande, R., et al. 2002. Mol. Cell Biol. 22, 1016.
Qiao, L., et al. 1999. J. Biol. Chem. 274, 10625.
Sun, X.J., et al. 1999. Diabetes 48, 1359.