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MABC151 Anti-Hyaluronan synthase 2 Antibody, clone 2B11.1

MABC151
100 µg  
Purchase on Sigma-Aldrich

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Replacement Information

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Kulcsspecifikációk táblázata

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWB, IH(P)MPurifiedMonoclonal Antibody
Description
Catalogue NumberMABC151
DescriptionAnti-Hyaluronan synthase 2 Antibody, clone 2B11.1
Alternate Names
  • Hyaluronan synthase 2
  • Hyaluronate synthase 2
  • Hyaluronic acid synthase 2
  • HA synthase 2
Background InformationHyaluronan synthase 2 (HAS2) is also known as Hyaluronate synthase 2, or Hyaluronic acid (HA) synthase 2. As the name suggests, HAS2 is involved in hyaluronan/hyaluronic acid synthesis. Hyaluronan synthase 2 is expressed in fibroblasts. Chromosomal aberrations involving Hyaluronan synthase 2 may be a cause of lipoblastomas, usually diagnosed in children.
References
Product Information
FormatPurified
Control
  • MRC-5 cell lysate
PresentationPurified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationDetect Hyaluronan synthase 2 using this mouse monoclonal antibody, Anti-Hyaluronan synthase 2 Antibody, clone 2B11.1 validated for use in western blotting & IHC (Paraffin).
Key Applications
  • Western Blotting
  • Immunohistochemistry (Paraffin)
Application NotesWestern Blotting Analysis: 2.0 µg/mL from a representative lot detected Hyaluronan synthase 2 in 10 µg of K562 cell lysate.
Immunohistochemistry Analysis: A 1:250 dilution from a representative lot detected Hyaluronan synthase 2 in human breast adenocarcinoma cell tissue.
Biological Information
ImmunogenGST-tagged recombinant protein corresponding to the cytoplasmic domain of human Hyaluronan synthase 2.
EpitopeCytoplasmic domain
Clone2B11.1
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostMouse
SpecificityThis antibody recognizes the cytoplasmic domain of Hyaluronan synthase 2.
IsotypeIgG2aκ
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • HAS2
Purification MethodProtein G Purified
UniProt Number
Molecular Weight~ 64 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in MRC-5 cell lysate.

Western Blotting Analysis: 0.2 µg/mL of this antibody detected Hyaluronan synthase 2 in 200 µg of MRC-5 cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalógusszám GTIN
MABC151 04053252907326