Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

ABS1035 Anti-FMO2 Antibody

Detect FMO2 using this Anti-FMO2 Antibody validated for use in Western Blotting, Immunohistochemistry.

Anti-FMO2 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Signaling Research Sub-Category: Toxicology & Drug Resistance Gene Symbol: FMO2, FMO1B1 UniProt Number: Q99518
ABS1035
200 µL  
Purchase on Sigma-Aldrich

Különleges ajánlatok

Áttekintés

Replacement Information

Különleges ajánlatok

100% Performance Guaranteed

Kulcsspecifikációk táblázata

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, MWB, IHCRbSerumPolyclonal Antibody
Description
Catalogue NumberABS1035
DescriptionAnti-FMO2 Antibody
Alternate Names
  • Dimethylaniline monooxygenase [N-oxide-forming] 2
  • Dimethylaniline oxidase 2
  • FMO 1B1
  • Pulmonary flavin-containing monooxygenase 2
  • FMO 2
Background InformationDimethylaniline monooxygenase [N-oxide-forming] 2 (EC 1.14.13.8; UniProt Q99518; also known as Dimethylaniline oxidase 2, FMO 1B1, FMO 2, Pulmonary flavin-containing monooxygenase 2) is encoded by the FMO2 (also known as FMO1B1) gene (Gene ID 2327) in human. Flavin monooxygenases (FMOs) are flavin-containing enzymes that catalyze substrates oxidation at the expense of NADPH and molecular oxygen. FMO2 is expressed in the lung tissue and therefore known as the pulmonary FMO. Two FMO2 alleles have been described in human. FMO2.1 is the functional full-length version that is found in high frequency in Sub-Saharan African populations (49%) and their Hispanic descendants (2-7%), whereas the FMO2.2 gene carries a C-to-T transition mutation that results in a premature stop codon (TAG), yielding a C-terminally truncated 64-amino acid non-functional protein FMO2X472 found in all Caucasians and Asians. Known human FMO2.1 substrates include sulfur-derived compounds such as thioureas, thioetherorganophosphates, thiazetazone and ethionamide.
References
Product Information
FormatSerum
PresentationRabbit polyclonal serum with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationDetect FMO2 using this Anti-FMO2 Antibody validated for use in Western Blotting, Immunohistochemistry.
Key Applications
  • Western Blotting
  • Immunohistochemistry
Application NotesImmunohistochemistry Analysis: A 1:50 dilution from a representative lot detected FMO2 in mouse lung, mouse kidney, and human kidney tissue sections.
Biological Information
ImmunogenLinear peptide corresponding to an internal sequence from the N-terminal half of human FMO2.
EpitopeInternal (N-terminal half).
ConcentrationPlease refer to lot specific datasheet.
HostRabbit
Species Reactivity
  • Human
  • Mouse
Species Reactivity NoteHuman, Mouse. Predicted to react with Chimpanzee, Orangutan based on 100% sequence homology.
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • FMO2
  • FMO1B1
Purification MethodUnpurified
UniProt Number
Molecular Weight~55 kDa observed. 53.64 kDa calculated.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in human liver microsomal lysate.

Western Blotting Analysis: A 1:500 dilution of this antibody detected FMO2 in 10 µg of human liver microsomal lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Packaging Information
Material Size200 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalógusszám GTIN
ABS1035 04055977315738