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ST1680 Anti-FGFR2 Mouse mAb (1G3)

Anti-FGFR2, mouse monoclonal, clone 1G3, recognizes the FDFR2 in human stomach carcinoma tissue. It is validated for use in ELISA, Western blotting, and immunohistochemistry (paraffin sections).

Anti-FGFR2 Mouse mAb (1G3) MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Anti-Fibroblast Growth Factor Receptor 2

ST1680
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Áttekintés

Replacement Information

Kulcsspecifikációk táblázata

Species ReactivityHostAntibody Type
HMMonoclonal Antibody

Products

KatalógusszámCsomagolás Menny./csomag
ST1680-100UG 100 μg
Description
OverviewRecognizes the FDFR2 protein in human stomach carcinoma tissue.
Catalogue NumberST1680
Brand Family Calbiochem®
SynonymsAnti-Fibroblast Growth Factor Receptor 2
References
Product Information
Formliquid
FormulationIn PBS, pH 7.2.
Positive controlHuman stomach carcinoma tissue
PreservativeNone
Quality LevelMQ100
Applications
Key Applications Enzyme-Linked Immunosorbent Assay
Immunoblotting (Western Blotting)
Paraffin Sections
Application NotesELISA (see comments) Immunoblotting (1-5 µg/ml) Paraffin Sections (5 µg/ml)
Application CommentsFor ELISA, this antibody can be used as the capture antibody; recommended concentration is 10 ng/ml, 1 µg/well, 100 µl total volume. Variables associated with assay conditions will dictate the proper working dilution.
Biological Information
ImmunogenA recombinant polypeptide corresponding to amino acids of 621-724 human FGFR2, supllied as a GST fusion protein
Clone1G3
HostMouse
IsotypeIgG2b
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Blue Ice Only
Toxicity Regulatory Review
Storage -20°C
Avoid freeze/thaw Avoid freeze/thaw
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalógusszám GTIN
ST1680-100UG 04055977223873

Documentation

Anti-FGFR2 Mouse mAb (1G3) MSDS

Title

Safety Data Sheet (SDS) 

Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision10-November-2010 RFH
SynonymsAnti-Fibroblast Growth Factor Receptor 2
ApplicationELISA (see comments) Immunoblotting (1-5 µg/ml) Paraffin Sections (5 µg/ml)
DescriptionPurified mouse monoclonal antibody. Recognizes the FDFR2 protein.
BackgroundThe protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. Mutations in this gene are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Beare-Stevenson cutis gyrata syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis. Multiple alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
HostMouse
ImmunogenA recombinant polypeptide corresponding to amino acids of 621-724 human FGFR2, supllied as a GST fusion protein
Clone1G3
IsotypeIgG2b
Specieshuman
Positive controlHuman stomach carcinoma tissue
Formliquid
FormulationIn PBS, pH 7.2.
PreservativeNone
CommentsFor ELISA, this antibody can be used as the capture antibody; recommended concentration is 10 ng/ml, 1 µg/well, 100 µl total volume. Variables associated with assay conditions will dictate the proper working dilution.
Storage Avoid freeze/thaw
-20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
Toxicity Regulatory Review