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MAB8702 Anti-Dengue Virus Type II Antibody, clone 3H5-1

MAB8702
100 µg  
Purchase on Sigma-Aldrich

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Species ReactivityKey ApplicationsHostFormatAntibody Type
HHI, IFMPurifiedMonoclonal Antibody
Description
Catalogue NumberMAB8702
Brand Family Chemicon®
Trade Name
  • Chemicon
DescriptionAnti-Dengue Virus Type II Antibody, clone 3H5-1
Background InformationDengue fever is an acute, mosquito-transmitted viral disease characterized by fever, headache, arthralgia (severe retro-orbital pain), myalgia, rash, nausea, and vomiting. Infections are caused by any of the four closely related, but antigenically distinct virus serotypes (DEN-1, DEN-2, DEN-3, and DEN-4). Infection with one of these serotypes does not provide cross-protective immunity, so persons living in a dengue-endemic area can have four dengue infections during their lifetimes. Dengue is primarily an urban disease of the tropics, and the viruses that cause it are maintained in a cycle that involves humans and Aedes aegypti, a domestic, day-biting mosquito that prefers to feed on humans. Although most dengue infections result in relatively mild illness, some can produce Dengue Hemorrhagic Fever (DHF) or dengue shock syndrome, with children being particularly at risk. Although epidemic outbreaks have been reported since 1779, the incidence has been increasing, with global, multiple serotype pandemics intensifying within the last 15 years. There is no specific antiviral therapy for dengue, but for both classical dengue and dengue hemorrhagic fever, symptomatic and supportive measures are effective. Important risk factors for DHF include the strain and serotype of the virus involved, as well as the age, immune status, and genetic predisposition of the patient.
Product Information
FormatPurified
Control
  • Dengue positive patient sample
PresentationProtein G Purified immunoglobulin. Liquid in 0.02 M PB, 0.25 M NaCl, pH = 7.6 with 0.1% Na Azide as a preservative
Quality LevelMQ300
Applications
ApplicationThis Anti-Dengue Virus Type II Antibody, clone 3H5-1 is validated for use in HI, IF for the detection of Dengue Virus Type II.
Key Applications
  • Hemagglutination Inhibition
  • Immunofluorescence
Application NotesRecommended for use in an immunofluorescent assay. Also suitable for use in hemagglutination-inhibition tests and plaque-reduction assays.

IFA: 1:200-1:400.

Dilute with buffer pH 7.5-8.0 to desired working volumes. For extensive dilution, protein containing or other stabilizing medium should be used.

Final working dilutions must be determined by end user.
Biological Information
ImmunogenDengue type 2 antigen (New Guinea C).
Clone3H5-1
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostMouse
SpecificityReacts with the Dengue type 2 virus.
IsotypeIgG1
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Purification MethodProtein G Purified
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintain at 2°C to 8°C in undiluted aliquots for up to 12 months after date of receipt.
Packaging Information
Material Size100 µg
Global Trade Item Number
Katalógusszám GTIN
MAB8702 04053252666469