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MABN491 Anti-Brevican Antibody, clone N294A/6

Anti-Brevican, clone N294A/6 is an antibody targeting the Brevican protein, validated for use in WB & IHC.

Anti-Brevican Antibody, clone N294A/6 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Developmental Neuroscience Gene Symbol: Bcan, Behab UniProt Number: P55068
MABN491
100 µg  
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Species ReactivityKey ApplicationsHostFormatAntibody Type
H, RWB, IHCMPurifiedMonoclonal Antibody
Description
Catalogue NumberMABN491
DescriptionAnti-Brevican Antibody, clone N294A/6
Alternate Names
  • Brevican core protein
  • Brain-enriched hyaluronan-binding protein
  • BEHAB
  • Brevican
Background InformationBrevican core protein (BCAN), also known as Brain-enriched hyaluronan-binding protein (BEHAB) or Chondroitin sulfate proteoglycan 7 (CSPG7), may play a role in the terminally differentiating and the adult nervous system during postnatal development. It may stabilize interactions between hyaluronan (HA) and brain proteoglycans. Two isoforms exist, with isoform 1 (~99 kDa) being highly expressed from birth through 8 years of age and down-regulated by 20 years of age to low levels that are maintained in the normal adult cortex; and isoform 2 (~72 kDa) being expressed at uniformly low levels throughout development.
References
Product Information
FormatPurified
Control
  • Rat brain tissue lysate
PresentationPurified mouse monoclonal IgG2bκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-Brevican, clone N294A/6 is an antibody targeting the Brevican protein, validated for use in WB & IHC.
Key Applications
  • Western Blotting
  • Immunohistochemistry
Application NotesWestern Blot Analysis: 2 µg/mL from a representative lot detected Brevican in 10 µg of human brain tissue lysate.

Immunohistochemistry Analysis: A 1:500 dilution from a representative lot detected Brevican in rat midbrain, rat thalamus, and rat cerebellum tissues.

Western Blot Analysis: A representative lot detected Brevican in rat brain tissue lysate and in WT, but not in Brevican knockout mouse brain tissue lysate.
Biological Information
ImmunogenRecombinant protein corresponding to rat Brevican.
CloneN294A/6
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostMouse
IsotypeIgG2bκ
Species Reactivity
  • Human
  • Rat
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • Bcan
  • Behab
Purification MethodProtein G Purified
UniProt Number
Molecular Weight~140 kDa observed. The calculated molecular weight of this protein is 96 kDa. A second isoform is known to exist at 69 kDa. This protein may be observed at a higher molecular weight due to glycosylation. A proteolyticaly cleaved fragment of Brevican may be observed at ~50 kDa in some tissue lysates.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blot in rat brain tissue lysate.

Western Blot Analysis: 2 µg/mL of this antibody detected Brevican in 10 µg of rat brain tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalógusszám GTIN
MABN491 04053252830822

Documentation

Anti-Brevican Antibody, clone N294A/6 MSDS

Title

Safety Data Sheet (SDS) 

Anti-Brevican Antibody, clone N294A/6 Certificates of Analysis

TitleLot Number
Anti-Brevican, clone N294A/6 3082491
Anti-Brevican, clone N294A/6 - 2499191 2499191
Anti-Brevican, clone N294A/6 - 3239890 3239890
Anti-Brevican, clone N294A/6 - 3462115 3462115
Anti-Brevican, clone N294A/6 - 4081237 4081237
Anti-Brevican, clone N294A/6 - 4167108 4167108
Anti-Brevican, clone N294A/6 - Q2107392 Q2107392
Anti-Brevican, clone N294A/6 -2523223 2523223
Anti-Brevican, clone N294A/6 -2584443 2584443
Anti-Brevican, clone N294A/6 -2821656 2821656
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