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ABC339 Anti-BFL-1 Antibody

ABC339
100 µg  
Purchase on Sigma-Aldrich

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Áttekintés

Replacement Information

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Kulcsspecifikációk táblázata

Species ReactivityKey ApplicationsHostFormatAntibody Type
MWB, IHC, IFRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABC339
DescriptionAnti-BFL-1 Antibody
Alternate Names
  • Bcl-2-related protein A1
  • Bcl-2-like protein 5
  • Bcl2-L-5
  • Hemopoietic-specific early response protein
  • Protein BFL-1
  • Protein GRS
  • BFL-1
Background InformationProtein BFL-1, also known as protein GRS, Bcl-2-like protein 5 (Bcl2-L-5), and Bcl-2-related protein A1 (BCL2A1), is a member of the Bcl-2 family. BFL-1 can interact with Bax and suppress apoptosis by inhibiting the release of cytochrome c and caspase-3 activation. BFL-1 is expressed in peripheral blood, spleen, bone marrow, lung, small intestine, and testis.
References
Product Information
FormatAffinity Purified
Control
  • Mouse kidney tissue lysate
PresentationPurified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-BFL-1 Antibody is a highly specific rabbit polyclonal antibody, that targets Bcl-2-related protein A1 & has been tested in western blotting, IHC & Immunofluorescence.
Key Applications
  • Western Blotting
  • Immunohistochemistry
  • Immunofluorescence
Application NotesImmunohistochemistry Analysis: 2 µg/mL from a representative lot detected BFL-1 in mouse kidney tissue.

Immunofluorescence Analysis: 20 µg/mL from a representative lot detected BFL-1 in mouse kidney cells.
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to the N-terminus of human BFL-1.
EpitopeN-terminus
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
SpecificityThis antibody recognizes the N-terminus of BFL-1.
Species Reactivity
  • Mouse
Species Reactivity NoteDemonstrated to react with Mouse. Predicted to react with Human based on immunogen design.
Antibody TypePolyclonal Antibody
Gene Symbol
  • BCL2A1
  • BCL2L5
  • BFL1
  • GRS
  • HBPA1
Purification MethodAntigen Affinity Purified
UniProt Number
Molecular Weight~39 kDa observed. Uniprot describes two isoforms at ~19 kDa and ~20 kDa.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in mouse kidney tissue lysate.

Western Blotting Analysis: 1 µg/mL of this antibody detected BFL-1 in 15 µg of mouse kidney tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalógusszám GTIN
ABC339 04053252901362