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ABC426 Anti-ATP-citrate synthase/ACLY Antibody

Anti-ATP-citrate synthase/ACLY Antibody | ABC426 is an antibody against ATP-citrate synthase/ACLY Antibody for use in Western Blotting, Immunohistochemistry.

Anti-ATP-citrate synthase/ACLY Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Apoptosis & Cancer Research Sub-Category: Apoptosis - Additional Gene Symbol: ACLY UniProt Number: P53396
ABC426
100 µL  
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Species ReactivityKey ApplicationsHostFormatAntibody Type
H, R, MWB, IHCRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABC426
DescriptionAnti-ATP-citrate synthase/ACLY Antibody
Alternate Names
  • ATP-citrate synthase
  • ATP-citrate (pro-S-)-lyase
  • ACL
  • Citrate cleavage enzyme
Background InformationATP citrate synthase, also known as ATP-citrate (pro-S-)-lyase (ACL) or Citrate cleavage enzyme, and encoded by the gene name ACLY is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine.
References
Product Information
FormatAffinity Purified
PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-ATP-citrate synthase/ACLY Antibody | ABC426 is an antibody against ATP-citrate synthase/ACLY Antibody for use in Western Blotting, Immunohistochemistry.
Key Applications
  • Western Blotting
  • Immunohistochemistry
Application NotesImmunohistochemistry Analysis: A 1:250 dilution from a representative lot detected ATP-citrate synthase/ACLY in human pancreas and human prostate tissue.
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to human ATP-citrate synthase/ACLY.
EpitopeUnknown
ConcentrationPlease refer to lot specific datasheet.
HostRabbit
Species Reactivity
  • Human
  • Rat
  • Mouse
Species Reactivity NoteHuman, Rat, Mouse. Predicted to react with Porcine, Bovine, Sheep based on 100% sequence homology.
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • ACLY
Purification MethodAffinity Purfied
UniProt Number
Molecular Weight~120 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in A549 cell lysate.

Western Blotting Analysis: A 1:1,000 dilution of this antibody detected ATP-citrate synthase/ACLY in 10 µg of A549 cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalógusszám GTIN
ABC426 04055977123739