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14-840 AMPK (α1, β1, γ1) Protein, active, 10 µg

Active, recombinant, human AMPK (α1, β1, γ1) holoenzyme, comprised of full length N-terminal 6His-tagged AMPKα1, full length untagged AMPKβ1 & full length untagged AMPKγ1. For use in Kinase Assays.

AMPK (α1, β1, γ1) Protein, active, 10 µg MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
14-840
10 µg  Also available in 250µg size as catalog # 14-840M - Call for pricing and availability.
Purchase on Sigma-Aldrich

Áttekintés

Replacement Information
Description
Catalogue Number14-840
Brand Family Upstate
Trade Name
  • Upstate
DescriptionAMPK (α1, β1, γ1) Protein, active, 10 µg
OverviewRecombinant, human AMPK (α1, β1, γ1) holoenzyme, comprised of full length N-terminal 6His-tagged AMPKα1, full length untagged AMPKβ1 and full length untagged AMPKγ1.
References
Product Information
Quality LevelMQ100
Applications
ApplicationActive, recombinant, human AMPK (α1, β1, γ1) holoenzyme, comprised of full length N-terminal 6His-tagged AMPKα1, full length untagged AMPKβ1 & full length untagged AMPKγ1. For use in Kinase Assays.
Key Applications
  • Kinase Assay
Biological Information
SourceExpressed in E. coli cells and activated in vivo.
Specific ActivityFor Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Entrez Gene Number
Entrez Gene SummaryThe protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Gene Symbol
  • PRKAB1
  • PRKAG1
  • PRKAA1
Protein TargetAMPK (α1, β1, γ1)
Purification MethodCobalt-agarose
Target Sub-FamilyCAMK
UniProt Number
Molecular WeightAMPKα1 MW = 64 kDa, AMPKß1 MW = 30 kDa, AMPKγ1 MW = 38 kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceRoutinely evaluated by phosphorylation of substrate peptide
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions6 months at -70°C
Packaging Information
Material Size10 µg
Material PackageAlso available in 250µg size as catalog # 14-840M - Call for pricing and availability.
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalógusszám GTIN
14-840 04053252514395

Documentation

AMPK (α1, β1, γ1) Protein, active, 10 µg MSDS

Title

Safety Data Sheet (SDS) 

AMPK (α1, β1, γ1) Protein, active, 10 µg Certificates of Analysis

TitleLot Number
AMPK (#945;1, #946;1, #947;1), active - 1767740-C 1767740-C
AMPK (#945;1, #946;1, #947;1), active - 1767740-D 1767740-D
AMPK (#945;1, #946;1, #947;1), active - 1767740-E 1767740-E
AMPK (#945;1, #946;1, #947;1), active - 1767740-F 1767740-F
AMPK (α1, β1, γ1), active - 1767740-G 1767740-G

Brochure

Title
Product Selection Guide - Antibodies, small molecule inhibitors, kits, assays and proteins for signaling research.

Kapcsolódó termékek és alkalmazások

Alternative Packsize

Katalógusszám Leírás
14-840M AMPK (α1, β1, γ1) Protein, active, 250 µg

Product Families

Kinase & Phosphatase Products

Millipore offers a large portfolio of Kinases, Phophatases, Substrates, Inhibitors, Kits, reagents & tools for Signaling research. See below for a list of these products, in multiple pack sizes.
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AMPK Antibodies, Kits & Proteins

Millipore’s AMPK Antibodies demonstrate specificity against AMP-activated protein kinase, which regulates metabolism. See below related products, based on the expertise of Upstate & Chemicon.
További információk >>

Kategóriák

Life Science Research > Proteins and Enzymes > Purified Kinases
Life Science Research > Drug Discovery and Development > Kinase & Phosphatase Screening > Purified Kinases