Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

PF121 α-Sarcin, Aspergillus giganteus

Native α-sarcin from Aspergillus giganteus.

α-Sarcin, Aspergillus giganteus MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
PF121
  
Purchase on Sigma-Aldrich

Áttekintés

Replacement Information

Kulcsspecifikációk táblázata

CAS #
86243-64-3
Description
Overview

This product has been discontinued.






Native α-sarcin from Aspergillus giganteus. α-Sarcin is a ribosome-inactivating protein that has been shown to induce apoptosis in rhabdomyosarcoma cells. Suitable for induction of apoptosis and inhibition of protein synthesis.
Catalogue NumberPF121
Brand Family Calbiochem®
References
ReferencesOlma, N., et al. 2001. Eur. J. Biochem. 268, 2113.
Product Information
CAS number86243-64-3
FormLyophilized
Applications
Biological Information
Purity≥95% by SDS-PAGE
Physicochemical Information
ContaminantsA trace amount of the dimeric form.
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R PhraseR: 42

May cause sensitization by inhalation.
S PhraseS: 36

Wear suitable protective clothing.
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Irritant
Storage ≤ -70°C
Avoid freeze/thaw Avoid freeze/thaw
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C). Stock solutions are stable for up to 6 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalógusszám GTIN
PF121 0

Documentation

α-Sarcin, Aspergillus giganteus MSDS

Title

Safety Data Sheet (SDS) 

α-Sarcin, Aspergillus giganteus Certificates of Analysis

TitleLot Number
PF121

References

Hivatkozások áttekintése
Olma, N., et al. 2001. Eur. J. Biochem. 268, 2113.

Brochure

Title
Caspases and other Apoptosis Related Tools Brochure
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision16-September-2008 RFH
DescriptionNative α-sarcin from Aspergillus giganteus. The mold Aspergillus giganteus produces a cytotoxic protein, α-sarcin, which inhibits protein synthesis by inactivating ribosomes. It selectively cleaves a single phosphodiester bond in a universally conserved sequence of the major rRNA to inactivate the ribosome and exert its cytotoxic action. While apoptosis is not a direct consequence of protein biosynthesis inhibition, it is related to the effects of the catalytic activity of the toxin on the ribosomes. Useful for Inhibition of protein synthesis and induction of apoptosis.
FormLyophilized
CAS number86243-64-3
Purity≥95% by SDS-PAGE
ContaminantsA trace amount of the dimeric form.
SolubilityH₂O (1 mg/ml)
Storage Avoid freeze/thaw
≤ -70°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C). Stock solutions are stable for up to 6 months at -20°C.
Toxicity Irritant
ReferencesOlma, N., et al. 2001. Eur. J. Biochem. 268, 2113.