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			96-Well Plate

数量	产品目录编号	订购说明	数量 / 包装	公开价
	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

554720 Milliporetrans-Retinoic Acid - CAS 302-79-4 - Calbiochem

Potent modulator of growth and differentiation. Inhibits melanocyte adhesion, motility, and growth.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书
参考
Data Sheet

同义词: Tretinoin, ATRA, Vitamin A Acid

Recommended Products

概述

Replacement Information

重要规格表

CAS #	Empirical Formula
302-79-4	C₂₀H₂₈O₂

价格及供货情况

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Description
Overview	Potent modulator of growth and differentiation. Exerts its effects by binding to nuclear retinoic acid receptors (RARs) which directly regulate gene expression. Inhibits melanocyte adhesion, motility, and growth. Has keratolytic activity. Induces differentiation of tumor cells of neural origin. Induces apoptosis in acute promyelocytic carcinoma cells. PROTECT FROM AIR.
Catalogue Number	554720
Brand Family	Calbiochem®
Synonyms	Tretinoin, ATRA, Vitamin A Acid

References
References	Tosi, P., et al. 1994. Leuk. Lymphoma 14, 503. Clagett-Dame, M., et al. 1993. Arch. Biochem. Biophys. 300, 684. Labbaye, C., et al. 1993. Blood 81, 475. Sakashita, A., et al. 1993. Blood 81, 1009. Situ, R., et al. 1993. Dermatology 186, 38. Tini, M., et al. 1993. Genes Develop. 7, 295. Leid, M., et al. 1992. Trends Biochem. Sci. 17, 427. Sharpe, C.R. 1991. Neuron 7, 239. Thaller, C. and Eichele, G. 1990. Nature 345, 815.

References

Tosi, P., et al. 1994. Leuk. Lymphoma 14, 503.
Clagett-Dame, M., et al. 1993. Arch. Biochem. Biophys. 300, 684.
Labbaye, C., et al. 1993. Blood 81, 475.
Sakashita, A., et al. 1993. Blood 81, 1009.
Situ, R., et al. 1993. Dermatology 186, 38.
Tini, M., et al. 1993. Genes Develop. 7, 295.
Leid, M., et al. 1992. Trends Biochem. Sci. 17, 427.
Sharpe, C.R. 1991. Neuron 7, 239.
Thaller, C. and Eichele, G. 1990. Nature 345, 815.

Product Information
CAS number	302-79-4
Form	Yellow solid
Hill Formula	C₂₀H₂₈O₂
Chemical formula	C₂₀H₂₈O₂
Hygroscopic	Hygroscopic
Structure formula Image
Quality Level	MQ100

Applications

Biological Information
Purity	≥95% by assay

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS
RTECS	VH6475000

Safety Information
R Phrase	R: 22-36/37/38-63 Harmful if swallowed. Irritating to eyes, respiratory system and skin. Possible risk of harm to the unborn child.
S Phrase	S: 22-26-36 Do not breathe dust. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing.

Product Usage Statements

Storage and Shipping Information
Ship Code	Ambient Temperature Only
Toxicity	Harmful & Carcinogenic / Teratogenic
Storage	+2°C to +8°C
Protect from Light	Protect from light
Hygroscopic	Hygroscopic
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution, store in the refrigerator (4°C). DMSO stock solutions are stable for up to 2 weeks at 4°C.

Packaging Information
Packaged under inert gas	Packaged under inert gas

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
554720-500MGCN	04061838431332

Documentation

trans-Retinoic Acid - CAS 302-79-4 - Calbiochem MSDS

职位
物料安全数据表 (MSDS)

trans-Retinoic Acid - CAS 302-79-4 - Calbiochem 分析证书

标题	批号
554720	输入批号

参考

参考信息概述
Tosi, P., et al. 1994. Leuk. Lymphoma 14, 503. Clagett-Dame, M., et al. 1993. Arch. Biochem. Biophys. 300, 684. Labbaye, C., et al. 1993. Blood 81, 475. Sakashita, A., et al. 1993. Blood 81, 1009. Situ, R., et al. 1993. Dermatology 186, 38. Tini, M., et al. 1993. Genes Develop. 7, 295. Leid, M., et al. 1992. Trends Biochem. Sci. 17, 427. Sharpe, C.R. 1991. Neuron 7, 239. Thaller, C. and Eichele, G. 1990. Nature 345, 815.

参考信息概述

数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	05-October-2007 RFH
Synonyms	Tretinoin, ATRA, Vitamin A Acid
Description	Potent modulator of growth and differentiation. Exerts its effects by binding to nuclear retinoic acid receptors (RARs) which directly regulate gene expression. Inhibits melanocyte adhesion, motility, and growth. Has keratolytic activity. Induces differentiation of tumor cells of neural origin. Induces apoptosis in acute promyelocytic carcinoma cells.
Form	Yellow solid
Intert gas (Yes/No)	Packaged under inert gas
CAS number	302-79-4
RTECS	VH6475000
Chemical formula	C₂₀H₂₈O₂
Structure formula
Purity	≥95% by assay
Solubility	DMSO (25 mg/ml)
Storage	Protect from light +2°C to +8°C Hygroscopic
Do Not Freeze	Ok to freeze
Special Instructions	Following reconstitution, store in the refrigerator (4°C). DMSO stock solutions are stable for up to 2 weeks at 4°C.
Toxicity	Harmful & Carcinogenic / Teratogenic
Merck USA index	14, 8165
References	Tosi, P., et al. 1994. Leuk. Lymphoma 14, 503. Clagett-Dame, M., et al. 1993. Arch. Biochem. Biophys. 300, 684. Labbaye, C., et al. 1993. Blood 81, 475. Sakashita, A., et al. 1993. Blood 81, 1009. Situ, R., et al. 1993. Dermatology 186, 38. Tini, M., et al. 1993. Genes Develop. 7, 295. Leid, M., et al. 1992. Trends Biochem. Sci. 17, 427. Sharpe, C.R. 1991. Neuron 7, 239. Thaller, C. and Eichele, G. 1990. Nature 345, 815.

种类

Life Science Research > Inhibitors and Biochemicals > Biochemicals > Vitamins, Coenzymes and Cofactors

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