数量	产品目录编号	订购说明	数量 / 包装	公开价
			96-Well Plate

数量	产品目录编号	订购说明	数量 / 包装	公开价
	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

677175 Sigma-AldrichVinblastine Sulfate - CAS 143-67-9 - Calbiochem

Antitumor alkaloid drug.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书
参考
小册子
Data Sheet

Primary Target: Interaction of tubulin with microtubule-associated proteins, specifically Tau and MAP2

Recommended Products

概述

Replacement Information

重要规格表

CAS #	Empirical Formula
143-67-9	C₄₆H₅₈N₄O₉ · H₂SO₄

价格及供货情况

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Description
Overview	Antitumor alkaloid drug. Induces apoptosis in cultured hepatocytes and human lymphoma cells. Affects interaction of tubulin with microtubule-associated proteins, specifically Tau and MAP2. Depolymerizes microtubules. Increases frequency of micronucleated erythrocytes.
Catalogue Number	677175
Brand Family	Calbiochem®

References
References	Tanaka, E., et al. 1995. J. Cell. Biol. 128, 139. Boscoboinik, D., et al. 1994. Biochem. Biophys. Res. Commun. 199, 374. Smith, C.D., et al. 1994. Cancer Lett. 79, 213. Smith, C.D., et al. 1994. Cancer Res. 54, 3779. Tsukidate, K., et al. 1993. Am. J. Pathol. 143, 198. Jagetia, G.C., and Jacob, P.S. 1992. Mutat. Res. 280, 87. Jordan, M.A., et al. 1992. J. Cell Sci. 102, 401. Prasad, V., et al. 1992. J. Protein Chem. 11, 509.

References

Tanaka, E., et al. 1995. J. Cell. Biol. 128, 139.
Boscoboinik, D., et al. 1994. Biochem. Biophys. Res. Commun. 199, 374.
Smith, C.D., et al. 1994. Cancer Lett. 79, 213.
Smith, C.D., et al. 1994. Cancer Res. 54, 3779.
Tsukidate, K., et al. 1993. Am. J. Pathol. 143, 198.
Jagetia, G.C., and Jacob, P.S. 1992. Mutat. Res. 280, 87.
Jordan, M.A., et al. 1992. J. Cell Sci. 102, 401.
Prasad, V., et al. 1992. J. Protein Chem. 11, 509.

Product Information
CAS number	143-67-9
ATP Competitive	N
Form	White crystalline solid
Hill Formula	C₄₆H₅₈N₄O₉ · H₂SO₄
Chemical formula	C₄₆H₅₈N₄O₉ · H₂SO₄
Reversible	N
Structure formula Image
Quality Level	MQ100

Applications

Biological Information
Primary Target	Interaction of tubulin with microtubule-associated proteins, specifically Tau and MAP2
Purity	≥98% by HPLC

Physicochemical Information
Cell permeable	N

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS
RTECS	YY8400000

Safety Information
R Phrase	R: 22-37/38-61-41 Harmful if swallowed. Irritating to respiratory system and skin. May cause harm to the unborn child. Risk of serious damage to eyes.
S Phrase	S: 22-26-36/37/39-45 Do not breathe dust. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing, gloves and eye/face protection. In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).

Product Usage Statements

Storage and Shipping Information
Ship Code	Ambient Temperature Only
Toxicity	Harmful & Carcinogenic / Teratogenic
Storage	+2°C to +8°C
Protect from Light	Protect from light
Protect from Moisture	Protect from moisture
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Packaging Information

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
677175-10MGCN	04055977260595

Documentation

Vinblastine Sulfate - CAS 143-67-9 - Calbiochem MSDS

职位
物料安全数据表 (MSDS)

Vinblastine Sulfate - CAS 143-67-9 - Calbiochem 分析证书

标题	批号
677175	输入批号

参考

参考信息概述
Tanaka, E., et al. 1995. J. Cell. Biol. 128, 139. Boscoboinik, D., et al. 1994. Biochem. Biophys. Res. Commun. 199, 374. Smith, C.D., et al. 1994. Cancer Lett. 79, 213. Smith, C.D., et al. 1994. Cancer Res. 54, 3779. Tsukidate, K., et al. 1993. Am. J. Pathol. 143, 198. Jagetia, G.C., and Jacob, P.S. 1992. Mutat. Res. 280, 87. Jordan, M.A., et al. 1992. J. Cell Sci. 102, 401. Prasad, V., et al. 1992. J. Protein Chem. 11, 509.

参考信息概述

小册子

标题
Tools and Tips for Analyzing Apoptosis

数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	31-July-2014 JSW
Description	Antitumor alkaloid drug. Induces apoptosis in cultured hepatocytes and human lymphoma cells. Affects interaction of tubulin with microtubule-associated proteins, specifically Tau and MAP2. Depolymerizes microtubules. Increases the frequency of micronucleated erythrocytes.
Form	White crystalline solid
CAS number	143-67-9
RTECS	YY8400000
Chemical formula	C₄₆H₅₈N₄O₉ · H₂SO₄
Structure formula
Purity	≥98% by HPLC
Solubility	H₂O (50 mg/ml)
Storage	Protect from moisture Protect from light +2°C to +8°C
Do Not Freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity	Harmful & Carcinogenic / Teratogenic
Merck USA index	14, 9982
References	Tanaka, E., et al. 1995. J. Cell. Biol. 128, 139. Boscoboinik, D., et al. 1994. Biochem. Biophys. Res. Commun. 199, 374. Smith, C.D., et al. 1994. Cancer Lett. 79, 213. Smith, C.D., et al. 1994. Cancer Res. 54, 3779. Tsukidate, K., et al. 1993. Am. J. Pathol. 143, 198. Jagetia, G.C., and Jacob, P.S. 1992. Mutat. Res. 280, 87. Jordan, M.A., et al. 1992. J. Cell Sci. 102, 401. Prasad, V., et al. 1992. J. Protein Chem. 11, 509.

种类

Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Extracellular Matrix, Adhesion and Cytoskeletal Research Tools

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