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676491 Sigma-AldrichVEGF Inducer, GS4012 - CAS 328073-92-3 - Calbiochem

A cell-permeable pyridinyl-thioether compound that acts as a potent inducer of VEGF and VEGF-mediated vessel formation.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书
参考
Data Sheet

同义词: 4-(2-(4-Methoxyphenylsulfanyl)ethyl)pyridine, HCl, GS4012

Primary Target: Potent inducer of VEGF and VEGF-mediated vessel formation

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概述

Replacement Information

重要规格表

CAS #	Empirical Formula
328073-92-3	C₁₄H₁₅NOS • HCl

价格及供货情况

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Description
Overview	A cell-permeable pyridinyl-thioether compound that acts as a potent inducer of VEGF and VEGF-mediated vessel formation. GS4012-induced upregulation of VEGF correlates well with its ability to suppress the gridlock/coarctation phenotype (7.5 µg/ml) in Zebrafish and to stimulate tubule network formation (5 µg/ml) in HUVECs.
Catalogue Number	676491
Brand Family	Calbiochem®
Synonyms	4-(2-(4-Methoxyphenylsulfanyl)ethyl)pyridine, HCl, GS4012

References
References	Peterson, R.T., et al. 2004. Nat. Biotechnol. 22, 595. Depre, C., et al. 2003. Circulation 108, 2723.

Product Information
CAS number	328073-92-3
ATP Competitive	N
Form	White solid
Hill Formula	C₁₄H₁₅NOS • HCl
Chemical formula	C₁₄H₁₅NOS • HCl
Hygroscopic	Hygroscopic
Reversible	N
Structure formula Image
Quality Level	MQ100

Applications

Biological Information
Primary Target	Potent inducer of VEGF and VEGF-mediated vessel formation
Purity	≥95% by HPLC

Physicochemical Information
Cell permeable	Y

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Toxicity	Standard Handling
Storage	+2°C to +8°C
Protect from Light	Protect from light
Hygroscopic	Hygroscopic
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Packaging Information
Packaged under inert gas	Packaged under inert gas

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
676491-10MGCN	04055977183672

Documentation

VEGF Inducer, GS4012 - CAS 328073-92-3 - Calbiochem MSDS

职位
物料安全数据表 (MSDS)

VEGF Inducer, GS4012 - CAS 328073-92-3 - Calbiochem 分析证书

标题	批号
676491	输入批号

参考

参考信息概述
Peterson, R.T., et al. 2004. Nat. Biotechnol. 22, 595. Depre, C., et al. 2003. Circulation 108, 2723.

数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	30-October-2023 JSW
Synonyms	4-(2-(4-Methoxyphenylsulfanyl)ethyl)pyridine, HCl, GS4012
Description	A cell-permeable and potent inducer of VEGF and VEGF-mediated blood vessel formation. GS4012-induced upregulation of VEGF correlates with its ability to suppress the gridlock/coarctation phenotype (7.5 µg/ml) in Zebrafish and to stimulate tubule network formation (5 µg/ml) in HUVECs. An essential molecule required during angioblasts cell fate determination.
Form	White solid
Intert gas (Yes/No)	Packaged under inert gas
CAS number	328073-92-3
Chemical formula	C₁₄H₁₅NOS • HCl
Structure formula
Purity	≥95% by HPLC
Solubility	DMSO (200 mg/ml), water, or Methanol (50 mg/ml)
Storage	Protect from light +2°C to +8°C Hygroscopic
Do Not Freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Toxicity	Standard Handling
References	Peterson, R.T., et al. 2004. Nat. Biotechnol. 22, 595. Depre, C., et al. 2003. Circulation 108, 2723.

种类

Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Activators > Other Activators/Agonists

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