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			96-Well Plate

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672999 Sigma-AldrichV-ATPase Inhibitor, KM91104 - Calbiochem

V-ATPase Inhibitor, KM91104 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书
参考
Data Sheet

同义词: H+-ATPase Inhibitor

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概述

Replacement Information

重要规格表

Empirical Formula
C₁₄H₁₂N₂O₄

价格及供货情况

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Description
Overview	A cell-permeable, non-macrolide small molecule V-ATPase inhibitor that specifically targets the a3-b2 subunit protein protein interation of V-ATPase (IC₅₀ of 2.3 µM), in vitro. It is also shown to inhibit osteoclast resorption (IC₅₀ of 1.2 µM) on both synthetic hydroxyapatite surfaces and dentin slices in an in vitro osteoclast model, RANKL-differentiated RAW 264.7 cells, without significantly affecting RAW 264.7 cell viability or RANKL-mediated osteoclast differentiation.
Catalogue Number	672999
Brand Family	Calbiochem®
Synonyms	H+-ATPase Inhibitor

References
References	Kartner, N., et al. 2010. J. Biol. Chem. 285, 37476.

Product Information
Form	Off-white solid
Hill Formula	C₁₄H₁₂N₂O₄
Chemical formula	C₁₄H₁₂N₂O₄
Structure formula Image
Quality Level	MQ100

Applications

Biological Information
Purity	>98% by HPLC

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Shipped with Blue Ice or with Dry Ice
Toxicity	Standard Handling
Storage	-20°C
Protect from Light	Protect from light
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Packaging Information
Packaged under inert gas	Packaged under inert gas

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
672999-10MGCN	04055977184143

Documentation

V-ATPase Inhibitor, KM91104 - Calbiochem MSDS

职位
物料安全数据表 (MSDS)

V-ATPase Inhibitor, KM91104 - Calbiochem 分析证书

标题	批号
672999	输入批号

参考

参考信息概述
Kartner, N., et al. 2010. J. Biol. Chem. 285, 37476.

数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	28-April-2015 JSW
Synonyms	H+-ATPase Inhibitor
Description	A cell-permeable, non-macrolide small molecule V-ATPase inhibitor that specifically targets the a3-b2 subunit protein protein interation of V-ATPase (IC₅₀ of 2.3 µM), in vitro. It is also shown to inhibit osteoclast resorption (IC₅₀ of 1.2 µM) on both synthetic hydroxyapatite surfaces and dentin slices in an in vitro osteoclast model, RANKL-differentiated RAW 264.7 cells, without significantly affecting RAW 264.7 cell viability or RANKL-mediated osteoclast differentiation.
Form	Off-white solid
Intert gas (Yes/No)	Packaged under inert gas
Chemical formula	C₁₄H₁₂N₂O₄
Structure formula
Purity	>98% by HPLC
Solubility	DMSO (100 mg/ml)
Storage	Protect from light -20°C
Do Not Freeze	Ok to freeze
Special Instructions	Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity	Standard Handling
References	Kartner, N., et al. 2010. J. Biol. Chem. 285, 37476.

种类

Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > ATPase/GTPase Inhibitors > ATPase Inhibitors

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