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Native urokinase from human urine. A thrombolytic agent that converts plasminogen to plasmin. A mixture of high molecular weight (54 kDa) and low molecular weight (33 kDa) urokinase.
Note: 1 unit = 1 CTA unit = 0.7 Ploug units. 1 KU = 1000 units.
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
Revision
19-May-2008 RFH
Synonyms
uPA
Description
Native urokinase from human urine. A thrombolytic agent that converts plasminogen to plasmin. A mixture of high molecular weight (54 kDa) and low molecular weight (33 kDa) urokinase.
Form
White lyophilized solid
Formulation
Lyophilized from 200 mM mannitol, 100 mM NaCl, 50 mM Tris-HCl, 0.1% PEG, pH 7.5.
Source
Prepared from urine of individuals that have been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
CAS number
9039-53-6
RTECS
OB8900000
EC number
3.4.99.26
Specific activity
≥100,000 units/mg protein
Unit definition
One unit is defined as the amount of enzyme equal to an international standard tested by the fibrinolytic method of Johnson, et al.
Solubility
Reconstitute in distilled H₂O
Storage
-20°C
Do Not Freeze
Ok to freeze
Special Instructions
Following reconstitution, aliquot and freeze (-70°C). Stock solutions are stable for up to 6 months at -70°C.
