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662041 Sigma-AldrichU-73343 - CAS 142878-12-4 - Calbiochem

A cell-permeable analog of U-73122 that acts as a very weak inhibitor of phospholipase C. Suitable as a negative control.

U-73343 - CAS 142878-12-4 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书
参考
Data Sheet
Citations

同义词: 1-[6-((17β-3-Methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl]-2,5-pyrrolidinedione

Primary Target: Negative control of U-73122 in the inhibition of phospholipase C

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概述

Replacement Information

重要规格表

CAS #	Empirical Formula
142878-12-4	C₂₉H₄₂N₂O₃

价格及供货情况

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Description
Overview	A cell-permeable analog of U-73122 (Cat. No. 662035) that acts as a very weak inhibitor of phospholipase C. Suitable as a negative control.
Catalogue Number	662041
Brand Family	Calbiochem®
Synonyms	1-[6-((17β-3-Methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl]-2,5-pyrrolidinedione

References
References	Tatrai, A., et al. 1994. Biochim. Biophys. Acta 1224, 595. Bleasdale, J.E., et al. 1990. J. Pharmacol. Exp. Ther. 255, 756. Smith, R.J., et al. 1990. J. Pharmacol. Exp. Ther. 253, 688.

Product Information
CAS number	142878-12-4
ATP Competitive	N
Form	Off-white solid
Hill Formula	C₂₉H₄₂N₂O₃
Chemical formula	C₂₉H₄₂N₂O₃
Reversible	N
Structure formula Image
Quality Level	MQ100

Applications

Biological Information
Primary Target	Negative control of U-73122 in the inhibition of phospholipase C
Purity	≥98% by TLC

Physicochemical Information
Cell permeable	Y

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information
R Phrase	R: 36/37/38 Irritating to eyes, respiratory system and skin.
S Phrase	S: 26-36 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing.

Product Usage Statements

Storage and Shipping Information
Ship Code	Ambient Temperature Only
Toxicity	Irritant
Storage	+15°C to +30°C
Do not freeze	Ok to freeze
Special Instructions	For storage in chloroform, aliquot into single use volumes, evaporate to dryness under a stream of nitrogen and freeze (-20°C). DMSO stocks solutions are stable for up to 6 months at -20°C.

Packaging Information

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
662041-5MGCN	04055977261066

Documentation

U-73343 - CAS 142878-12-4 - Calbiochem MSDS

职位
物料安全数据表 (MSDS)

U-73343 - CAS 142878-12-4 - Calbiochem 分析证书

标题	批号
662041	输入批号

参考

参考信息概述
Tatrai, A., et al. 1994. Biochim. Biophys. Acta 1224, 595. Bleasdale, J.E., et al. 1990. J. Pharmacol. Exp. Ther. 255, 756. Smith, R.J., et al. 1990. J. Pharmacol. Exp. Ther. 253, 688.

引用

标题

Martha E. O'Donnnell, et al. (2005) Arginine Vasopressin Stimulation of Cerebral Microvascular Endothelial Cell Na-K-Cl Cotransporter Activity is V1 Receptor and [Ca] Dependent. American Journal of Physiology Cell Physiology 289, C283-C292.

Di Zhang, et al. (2005) Strontium Promotes Calcium Oscillations in Mouse Meiotic Oocytes and Early Embryos Through InsP3 Receptors, and Requires Activation of Phopsholipase and the Synertistic Action of InsP3. Human Reproduction in press,.

数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	20-February-2024 JSW
Synonyms	1-[6-((17β-3-Methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl]-2,5-pyrrolidinedione
Description	A cell-permeable analog of U-73122 (Cat. No. 662035) that acts as a very weak inhibitor of phospholipase C. Suitable as a negative control.
Form	Off-white solid
CAS number	142878-12-4
Chemical formula	C₂₉H₄₂N₂O₃
Structure formula
Purity	≥98% by TLC
Solubility	Chloroform (200 mg/ml), DMSO (2 mg/ml), or Ethanol (1 mg/ml)
Storage	+15°C to +30°C
Do Not Freeze	Ok to freeze
Special Instructions	For storage in chloroform, aliquot into single use volumes, evaporate to dryness under a stream of nitrogen and freeze (-20°C). DMSO stocks solutions are stable for up to 6 months at -20°C.
Toxicity	Irritant
References	Tatrai, A., et al. 1994. Biochim. Biophys. Acta 1224, 595. Bleasdale, J.E., et al. 1990. J. Pharmacol. Exp. Ther. 255, 756. Smith, R.J., et al. 1990. J. Pharmacol. Exp. Ther. 253, 688.
Citation	Martha E. O'Donnnell, et al. (2005) Arginine Vasopressin Stimulation of Cerebral Microvascular Endothelial Cell Na-K-Cl Cotransporter Activity is V1 Receptor and [Ca] Dependent. American Journal of Physiology Cell Physiology 289, C283-C292. Di Zhang, et al. (2005) Strontium Promotes Calcium Oscillations in Mouse Meiotic Oocytes and Early Embryos Through InsP3 Receptors, and Requires Activation of Phopsholipase and the Synertistic Action of InsP3. Human Reproduction in press,.

种类

Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Lipid Signaling Inhibitors > Phospholipase Inhibitors

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