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			96-Well Plate

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	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

612200 Sigma-AldrichTissue Plasminogen Activator, Human

Tissue Plasminogen Activator, Human MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书
参考
Data Sheet

同义词: tPA

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概述

Replacement Information

价格及供货情况

产品目录编号	库存情况	包装	数量 / 包装	价格	数量
612200-100UGCN	正在查询供货情况...... — 目前缺货有货停产少量现货供货情况有待确认登录查看库存有货目前缺货有货其余：另行通知其余：另行通知另行通知联系客户服务 Contact Customer Service 联系客户服务联系客户服务	塑胶安瓿;塑胶针药瓶	100 μg	正在检索价格...... 无法检索价格。最小订购数量为倍数 Maximum Quantity is 以订单确认为准更多信息您节约了 ()。 — Request Pricing 登录查看价格	查看库存情况 —	添加到收藏夹添加到收藏夹添加到我的收藏夹
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Description
Overview	Native tissue plasminogen activator from a human melanoma cell line. A serine protease that contains a single chain of 527 amino acids. Binds to fibrin via lysine binding sites at its amino terminus and activates bound plasminogen. Cleaves plasminogen to form active plasmin, the proteolytic enzyme that dissolves clots. Reported to be involved in neurite outgrowth, regeneration, and migration. Plays an important role in excitotoxin-induced neuronal degeneration.
Catalogue Number	612200
Brand Family	Calbiochem®
Synonyms	tPA

References
References	Kim, Y.H., et al. 1999. Science 284, 647. Tsirka, S.E., et al. 1995. Nature 377, 340. Winther, K., et al. 1992. J. Cardiovasc. Pharmacol. 19, S21.

Product Information
Form	Lyophilized
Formulation	Lyophilized from 100 mM PBS, 3.5 mg/ml L-arginine, 0.001% Tween^®-80 Detergent.
Quality Level	MQ100

Applications

Biological Information
Purity	≥95% by SDS-PAGE
Source	Prepared from cell line that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Specific Activity	≥300 KU/mg protein

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Blue Ice Only
Toxicity	Standard Handling
Storage	-20°C
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Packaging Information

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
612200-100UGCN	04055977187762
612200-1MGCN	04055977187755

Documentation

Tissue Plasminogen Activator, Human MSDS

职位
物料安全数据表 (MSDS)

Tissue Plasminogen Activator, Human 分析证书

标题	批号
612200	输入批号

参考

参考信息概述
Kim, Y.H., et al. 1999. Science 284, 647. Tsirka, S.E., et al. 1995. Nature 377, 340. Winther, K., et al. 1992. J. Cardiovasc. Pharmacol. 19, S21.

数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	17-May-2011 JSW
Synonyms	tPA
Description	Native tissue plasminogen activator from a human melanoma cell line. A serine protease that contains a single chain of 527 amino acid residues. Binds to fibrin via lysine binding sites at its amino terminus and activates bound plasminogen. Cleaves plasminogen to form active plasmin, the proteolytic enzyme that dissolves clots. Reported to be involved in neurite outgrowth, regeneration, and migration. Plays an important role in excitotoxin-induced neuronal degeneration. Dihydropyridine Ca²⁺ antagonist may increase levels of tPA.
Form	Lyophilized
Formulation	Lyophilized from 100 mM PBS, 3.5 mg/ml L-arginine, 0.001% Tween^®-80 Detergent.
Source	Prepared from cell line that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Purity	≥95% by SDS-PAGE
Specific activity	≥300 KU/mg protein
Solubility	Reconstitute with diH₂O to a final concentration of 1 mg/ml (e.g., 100 µg should be reconstituted in 100 µl).
Storage	-20°C
Do Not Freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Toxicity	Standard Handling
References	Kim, Y.H., et al. 1999. Science 284, 647. Tsirka, S.E., et al. 1995. Nature 377, 340. Winther, K., et al. 1992. J. Cardiovasc. Pharmacol. 19, S21.

种类

Life Science Research > Proteins and Enzymes > Other Enzymes

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