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			96-Well Plate

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	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

605197 Sigma-AldrichThrombin-Activatable Fibrinolysis Inhibitor, Human

The Thrombin-Activatable Fibrinolysis Inhibitor, Human controls the biological activity of Thrombin-Activatable Fibrinolysis. This small molecule/inhibitor is primarily used for Biochemicals applications.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书
参考
Data Sheet

同义词: Plasma Procarboxypeptidase B, TAFI

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概述

Replacement Information

价格及供货情况

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Description
Overview	Native thrombin-activatable fibrinolysis inhibitor from human liver. Single chain glycoprotein synthesized in the liver. Circulates in plasma as a zymogen at a concentration of 50 nM. Activated by thrombin-thrombomodulin complex by proteolytic cleavage at Arg⁹². Believed to play an important role in interaction between the procoagulant, anticoagulant, and fibrinolytic systems.
Catalogue Number	605197
Brand Family	Calbiochem®
Synonyms	Plasma Procarboxypeptidase B, TAFI

References
References	Boffa, M.B., et al. 1999. Biochemistry 38, 6547. Boffa, M.B., et al. 1998. J. Biol. Chem. 273, 2127. Bajzar, L., et al. 1995. J. Biol. Chem. 270, 14477.

Product Information
Unit of Definition	One unit is defined as the amount of enzyme that will hydrolyze 1 µM Hip-L-Arg per min at 25°C, pH 7.65.
Form	Liquid
Formulation	In 150 mM NaCl, 20 mM HEPES, pH 7.4.
Quality Level	MQ100

Applications

Biological Information
Purity	≥95% by SDS-PAGE
Source	Prepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Specific Activity	≥2-9 units/mg protein
Concentration Label	Please refer to vial label for lot-specific concentration

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Dry Ice Only
Toxicity	Standard Handling
Storage	≤ -70°C
Do not freeze	Ok to freeze
Special Instructions	Following initial thaw, aliquot and freeze (-70°C).

Packaging Information

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
605197-50UGCN	04055977188431

Documentation

Thrombin-Activatable Fibrinolysis Inhibitor, Human MSDS

职位
物料安全数据表 (MSDS)

Thrombin-Activatable Fibrinolysis Inhibitor, Human 分析证书

标题	批号
605197	输入批号

参考

参考信息概述
Boffa, M.B., et al. 1999. Biochemistry 38, 6547. Boffa, M.B., et al. 1998. J. Biol. Chem. 273, 2127. Bajzar, L., et al. 1995. J. Biol. Chem. 270, 14477.

数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	12-November-2007 JSW
Synonyms	Plasma Procarboxypeptidase B, TAFI
Description	Native thrombin-activatable fibrinolysis inhibitor from human liver. Single chain glycoprotein synthesized in the liver. ctivated by the thrombin/thrombomodulin complex by proteolytic cleavage at Arg⁹². Circulates in plasma as a zymogen at a concentration of about 50 nM. Believed to play an important role in the interaction between procoagulant, anticoagulant, and fibrinolytic systems.
Form	Liquid
Formulation	In 150 mM NaCl, 20 mM HEPES, pH 7.4.
Concentration Label	Please refer to vial label for lot-specific concentration
Source	Prepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Purity	≥95% by SDS-PAGE
Specific activity	≥2-9 units/mg protein
Unit definition	One unit is defined as the amount of enzyme that will hydrolyze 1 µM Hip-L-Arg per min at 25°C, pH 7.65.
Storage	≤ -70°C
Do Not Freeze	Ok to freeze
Special Instructions	Following initial thaw, aliquot and freeze (-70°C).
Toxicity	Standard Handling
References	Boffa, M.B., et al. 1999. Biochemistry 38, 6547. Boffa, M.B., et al. 1998. J. Biol. Chem. 273, 2127. Bajzar, L., et al. 1995. J. Biol. Chem. 270, 14477.

种类

Life Science Research > Proteins and Enzymes > Other Enzymes

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