573096 Sigma-AldrichSTAT3 Inhibitor Peptide, Cell-Permeable
STAT3 Inhibitor Peptide, Cell-Permeable, is an analog of Stat3-SH2 domain-binding phosphopeptide with a C-terminal membrane translocating sequence. A selective, potent blocker of Stat3 activation.
More>> STAT3 Inhibitor Peptide, Cell-Permeable, is an analog of Stat3-SH2 domain-binding phosphopeptide with a C-terminal membrane translocating sequence. A selective, potent blocker of Stat3 activation. Less<<STAT3 Inhibitor Peptide, Cell-Permeable MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
同义词: PpYLKTK-mts, STAT3 Inhibitor IV
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概述
| Replacement Information |
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重要规格表
| Empirical Formula |
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| C₉₂H₁₅₇N₂₀O₂₄P |
价格及供货情况
| 产品目录编号 | 库存情况 | 包装 | 数量 / 包装 | 价格 | 数量 | |
|---|---|---|---|---|---|---|
| 573096-1MGCN |
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塑胶安瓿;塑胶针药瓶 | 1 mg |
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— | |
| 573096-5MGCN |
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塑胶安瓿;塑胶针药瓶 | 5 mg |
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| Description | |
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| Overview | A cell-permeable analog of the Stat3-SH2 domain-binding phosphopeptide (Cat. No. 573095) that contains a C-terminal mts (membrane translocating sequence) and acts as a highly selective, potent blocker of Stat3 activation. Also suppresses constitutive Stat-3 dependent Src transformation with no effect on Stat-3 independent Ras transformation. The unphosphorylated inactive control peptide is also available under Cat. No. 573105. |
| Supplied as a trifluoroacetate salt. | |
| Catalogue Number | 573096 |
| Brand Family | Calbiochem® |
| Synonyms | PpYLKTK-mts, STAT3 Inhibitor IV |
| References | |
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| References | Turkson, J., et al. 2001. J. Biol. Chem. 276, 45443. Rojas, M., et al. 1998. Nat. Biotechnol. 16, 370. |
| Product Information | |
|---|---|
| ATP Competitive | N |
| Form | White lyophilized solid |
| Formulation | Supplied as a trifluoroacetate salt. |
| Hill Formula | C₉₂H₁₅₇N₂₀O₂₄P |
| Chemical formula | C₉₂H₁₅₇N₂₀O₂₄P |
| Hygroscopic | Hygroscopic |
| Reversible | N |
| Quality Level | MQ100 |
| Biological Information | |
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| Primary Target | Blocker of Stat3 activation |
| Purity | ≥95% by HPLC |
| Physicochemical Information | |
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| Cell permeable | Y |
| Peptide Sequence | H-Pro-Tyr-(PO₃H₂)-Leu-Lys-Thr-Lys-Ala-Ala-Val-Leu-Leu-Pro-Val-Leu-Leu-Ala-Ala-Pro-OH |
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| Materials Information |
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| Toxicological Information |
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| Safety Information according to GHS |
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| Safety Information |
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| Product Usage Statements |
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| Packaging Information | |
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| Packaged under inert gas | Packaged under inert gas |
| Transport Information |
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| Supplemental Information |
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| Specifications |
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| Global Trade Item Number | |
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| 产品目录编号 | GTIN |
| 573096-1MGCN | 07790788051730 |
| 573096-5MGCN | 07790788051747 |
Documentation
STAT3 Inhibitor Peptide, Cell-Permeable MSDS
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STAT3 Inhibitor Peptide, Cell-Permeable 分析证书
| 标题 | 批号 |
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| 573096 |
参考
| 参考信息概述 |
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| Turkson, J., et al. 2001. J. Biol. Chem. 276, 45443. Rojas, M., et al. 1998. Nat. Biotechnol. 16, 370. |
小册子
| 标题 |
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| An Introduction to Inhibitors and Their Biological Applications - 1st Edition |
技术信息
| 标题 |
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| JAK/STAT Signaling Research Focus |
引用
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