Custom Premix Selecting "Custom Premix" option means that all of the beads you have chosen will be premixed in manufacturing before the kit is sent to you.
A selective, competitive antagonist of GABAA receptor (IC50 = 440 nM) that does not affect pentobarbitone or etomidate- induced currents even at high concentrations (~100 µM). Also shown to block glycine receptors, but with low affinity (Kb = 190 µM).
Catalogue Number
505986
Brand Family
Calbiochem®
Synonyms
GABAA Receptor Antagonist, SR-95531, Gabazine, SR95531, SR 95531
References
References
Muroi, Y., et al. 2009. Biophys. J.96, 499. Beato, M., et al. 2007. J. Physiol.580, 171. Uchida, I., et al. 1996. Eur. J. Pharmacol.307, 89.
Muroi, Y., et al. 2009. Biophys. J.96, 499. Beato, M., et al. 2007. J. Physiol.580, 171. Uchida, I., et al. 1996. Eur. J. Pharmacol.307, 89.
数据表
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
Revision
20-September-2013 JSW
Synonyms
GABAA Receptor Antagonist, SR-95531, Gabazine, SR95531, SR 95531
Description
A selective, competitive antagonist of GABAA receptor (IC50 = 440 nM) that does not affect pentobarbitone or etomidate- induced currents even at high concentrations (~100 mM). Also shown to block glycine receptors, but with low affinity (Kb = 190 mM).
Form
White solid
CAS number
104104-50-9
Chemical formula
C₁₅H₁₇N₃O₃•HBr
Structure formula
Purity
≥98% by HPLC
Solubility
H₂O (25 mM)
Storage
Protect from light
+2°C to +8°C
Do Not Freeze
Ok to freeze
Special Instructions
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity
Standard Handling
References
Muroi, Y., et al. 2009. Biophys. J.96, 499. Beato, M., et al. 2007. J. Physiol.580, 171. Uchida, I., et al. 1996. Eur. J. Pharmacol.307, 89.
