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A very potent and selective δ opioid receptor agonist (IC50 = 0.32 µM). Shown to induce dose- and time-dependent antinociception after i.c.v., i.th. and i.p. administration in mice. Widely used in studies of depression and inflammatory injuries. It is also reported to be acted upon heteromeric u-d receptors.
Catalogue Number
508161
Brand Family
Calbiochem®
Synonyms
δ Opioid Receptor Agonist, SNC80
References
References
Pradhan, A., et al., 2013. Mol Pain.9, 8. Saitoh, A., et al., 2012. Curr. Neuropharmacol.10, 231. Metcalf. M. et al. 2012. ACS Chem. Neurosci.3, 505. Bilsky, J., et al. 1995. J. Pharmacol. Exp. Ther.273, 359.
Pradhan, A., et al., 2013. Mol Pain.9, 8. Saitoh, A., et al., 2012. Curr. Neuropharmacol.10, 231. Metcalf. M. et al. 2012. ACS Chem. Neurosci.3, 505. Bilsky, J., et al. 1995. J. Pharmacol. Exp. Ther.273, 359.
数据表
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
Revision
31-October-2013 JSW
Synonyms
δ Opioid Receptor Agonist, SNC80
Description
A very potent and selective δ opioid receptor agonist (IC50 = 0.32 µM). Shown to induce dose- and time-dependent antinociception after i.c.v., i.th. and i.p. administration in mice. Widely used in studies of depression and inflammatory injuries. It is also reported to be acted upon heteromeric u-d receptors.
Form
Cream solid
CAS number
156727-74-1
Chemical formula
C₂₈H₃₉N₃O₂
Structure formula
Purity
≥98% by HPLC
Solubility
DMSO (20 mM) or 1N HCl (100 mM)
Storage
Protect from light
-20°C
Do Not Freeze
Ok to freeze
Special Instructions
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity
Standard Handling
References
Pradhan, A., et al., 2013. Mol Pain.9, 8. Saitoh, A., et al., 2012. Curr. Neuropharmacol.10, 231. Metcalf. M. et al. 2012. ACS Chem. Neurosci.3, 505. Bilsky, J., et al. 1995. J. Pharmacol. Exp. Ther.273, 359.
