566313 Sigma-AldrichSIRT1 Activator II - CAS 374922-43-7 - Calbiochem
The SIRT1 Activator II, also referenced under CAS 374922-43-7, modulates the biological activity of SIRT1. This small molecule/inhibitor is primarily used for Biochemicals applications.
More>> The SIRT1 Activator II, also referenced under CAS 374922-43-7, modulates the biological activity of SIRT1. This small molecule/inhibitor is primarily used for Biochemicals applications. Less<<MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
同义词: 3-(Benzenesulfonyl)-1-(4-fluorophenyl)pyrrolo[4,5-b]quinoxalin-2-amine , CAY10602, SIRT1 Activator II
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概述
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重要规格表
| CAS # | Empirical Formula |
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| 374922-43-7 | C₂₂H₁₅FN₄O₂S |
价格及供货情况
| 产品目录编号 | 库存情况 | 包装 | 数量 / 包装 | 价格 | 数量 | |
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| 566313-10MGCN |
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玻璃瓶 | 10 mg |
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| Description | |
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| Overview | A cell-permeable pyrroloquinoxaline compound that acts as a reversible SIRT1 activator (10 µM causes ~2.3-fold fluorescent enhancement in a fluorescent assay using hrSIRT1) and enhances fat mobilization in fully differentiated 3T3L1 fibroblasts. Shown to inhibit LPS-induced TNF-α release in THP-1 cells by ~10-fold more potent than resveratrol (Cat. No. 554325). |
| Catalogue Number | 566313 |
| Brand Family | Calbiochem® |
| Synonyms | 3-(Benzenesulfonyl)-1-(4-fluorophenyl)pyrrolo[4,5-b]quinoxalin-2-amine , CAY10602, SIRT1 Activator II |
| References | |
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| References | Lavu, S., et al. 2008. Nat. Rev. Drug Discov. 7, 841. Nayagam, V.M., et al. 2006. J. Biomol. Screen. 11, 959. |
| Product Information | |
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| CAS number | 374922-43-7 |
| Form | Off-white powder |
| Hill Formula | C₂₂H₁₅FN₄O₂S |
| Chemical formula | C₂₂H₁₅FN₄O₂S |
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| Quality Level | MQ100 |
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| Purity | ≥98% by HPLC |
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| Packaged under inert gas | Packaged under inert gas |
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| Specifications |
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| Global Trade Item Number | |
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| 产品目录编号 | GTIN |
| 566313-10MGCN | 04055977191363 |
Documentation
SIRT1 Activator II - CAS 374922-43-7 - Calbiochem MSDS
| 职位 |
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SIRT1 Activator II - CAS 374922-43-7 - Calbiochem 分析证书
| 标题 | 批号 |
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| 566313 |
参考
| 参考信息概述 |
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| Lavu, S., et al. 2008. Nat. Rev. Drug Discov. 7, 841. Nayagam, V.M., et al. 2006. J. Biomol. Screen. 11, 959. |
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Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
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