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			96-Well Plate

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	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

559276 Sigma-AldrichRyanodine, High Purity - CAS 15662-33-6 - Calbiochem

Ryanodine, High Purity - CAS 15662-33-6, is a naturally occurring alkaloid that blocks the release of Ca2+ from the sarcoplasmic reticulum (IC50 = 10 nM for skeletal muscle).

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书
参考
Data Sheet

Primary Target: Ca2+ transport and action in muscle

Recommended Products

概述

Replacement Information

重要规格表

CAS #	Empirical Formula
15662-33-6	C₂₅H₃₅NO₉

价格及供货情况

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Description
Overview	Naturally occurring alkaloid that blocks the release of Ca²⁺ from the sarcoplasmic reticulum. Has many complex effects on Ca²⁺ transport and action in muscle.
Catalogue Number	559276
Brand Family	Calbiochem®

References
References	Sorrentino, V., and Volpe, P. 1993. Trends Pharmacol. Sci. 14, 98. Sabbadini, R., et al. 1992. J. Biol. Chem. 267, 15475. Feher, J.J., and Lipford, G.B. 1985. Biochim. Biophys. Acta 813, 77. Marban, E., and Wier, W.G. 1985. Circ. Res. 56, 133. Sukto, J.L., et al. 1985. Fed. Proc. 44, 2984.

Product Information
CAS number	15662-33-6
ATP Competitive	N
Form	White solid
Hill Formula	C₂₅H₃₅NO₉
Chemical formula	C₂₅H₃₅NO₉
Reversible	N
Structure formula Image
Quality Level	MQ100

Applications
Application	Ryanodine, High Purity - CAS 15662-33-6, is a naturally occurring alkaloid that blocks the release of Ca2+ from the sarcoplasmic reticulum (IC50 = 10 nM for skeletal muscle).

Biological Information
Primary Target	Ca2+ transport and action in muscle
Purity	≥98% by HPLC

Physicochemical Information
Cell permeable	N

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS
RTECS	VM4025000

Safety Information
R Phrase	R: 21/22-50/53 Harmful in contact with skin and if swallowed. Very toxic to aquatic organisms; may cause long-term adverse effects in the aquatic environment.
S Phrase	S: 36/37-60-61 Wear suitable protective clothing and gloves. This material and its container must be disposed of as hazardous waste. Avoid release to the environment. Refer to special instructions/safety data sheet.

Product Usage Statements

Storage and Shipping Information
Ship Code	Ambient Temperature Only
Toxicity	Harmful
Storage	+15°C to +30°C
Protect from Light	Protect from light
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution, refrigerate (4°C). Stock solutions are stable for up to 1 month at 4°C.

Packaging Information

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
559276-500UGCN	04055977192353

Documentation

Ryanodine, High Purity - CAS 15662-33-6 - Calbiochem MSDS

职位
物料安全数据表 (MSDS)

Ryanodine, High Purity - CAS 15662-33-6 - Calbiochem 分析证书

标题	批号
559276	输入批号

参考

参考信息概述
Sorrentino, V., and Volpe, P. 1993. Trends Pharmacol. Sci. 14, 98. Sabbadini, R., et al. 1992. J. Biol. Chem. 267, 15475. Feher, J.J., and Lipford, G.B. 1985. Biochim. Biophys. Acta 813, 77. Marban, E., and Wier, W.G. 1985. Circ. Res. 56, 133. Sukto, J.L., et al. 1985. Fed. Proc. 44, 2984.

数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	10-December-2007 JSW
Description	Naturally occurring alkaloid that blocks the release of Ca²⁺ from the sarcoplasmic reticulum. Has many complex effects on Ca²⁺ transport and action in muscle. Purified from Ryanodine Mixture.
Form	White solid
CAS number	15662-33-6
RTECS	VM4025000
Chemical formula	C₂₅H₃₅NO₉
Structure formula
Purity	≥98% by HPLC
Solubility	Methanol (20 mg/ml) or H₂O (1 mg/ml)
Storage	Protect from light +15°C to +30°C
Do Not Freeze	Ok to freeze
Special Instructions	Following reconstitution, refrigerate (4°C). Stock solutions are stable for up to 1 month at 4°C.
Toxicity	Harmful
Merck USA index	14, 8307
References	Sorrentino, V., and Volpe, P. 1993. Trends Pharmacol. Sci. 14, 98. Sabbadini, R., et al. 1992. J. Biol. Chem. 267, 15475. Feher, J.J., and Lipford, G.B. 1985. Biochim. Biophys. Acta 813, 77. Marban, E., and Wier, W.G. 1985. Circ. Res. 56, 133. Sukto, J.L., et al. 1985. Fed. Proc. 44, 2984.

种类

Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Calcium Signaling > Other Calcium Channel Modulators

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