数量	产品目录编号	订购说明	数量 / 包装	公开价
			96-Well Plate

数量	产品目录编号	订购说明	数量 / 包装	公开价
	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

516481 Sigma-AldrichPepstatin A, Synthetic - CAS 26305-03-3 - Calbiochem

Pepstatin A, Synthetic, CAS 26305-03-3, is a reversible inhibitor of aspartic proteases. Inhibits cathepsin D, pepsin, and renin.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书
参考
小册子
技术信息
Data Sheet

同义词: Iva-Val-Val-Sta-Ala-Sta, Isovaleryl-Val-Val-4-amino-3-hydroxy-6-methylheptanoyl-Ala-4-amino-3-hydroxy-6-methylheptanoic Acid

Primary Target: cathepsin D

View Products on Sigmaaldrich.com

Recommended Products

概述

Replacement Information

重要规格表

CAS #	Empirical Formula
26305-03-3	C₃₄H₆₃N₅O₉

价格及供货情况

产品目录编号	库存情况	包装	数量 / 包装	价格	数量
516481-100MGCN	正在查询供货情况...... — 目前缺货有货停产少量现货供货情况有待确认登录查看库存有货目前缺货有货其余：另行通知其余：另行通知另行通知联系客户服务 Contact Customer Service 联系客户服务联系客户服务	塑胶安瓿;塑胶针药瓶	100 mg	正在检索价格...... 无法检索价格。最小订购数量为倍数 Maximum Quantity is 以订单确认为准更多信息您节约了 ()。 — Request Pricing 登录查看价格	查看库存情况 —	添加到收藏夹添加到收藏夹添加到我的收藏夹
516481-25MGCN	正在查询供货情况...... — 目前缺货有货停产少量现货供货情况有待确认登录查看库存有货目前缺货有货其余：另行通知其余：另行通知另行通知联系客户服务 Contact Customer Service 联系客户服务联系客户服务	塑胶安瓿;塑胶针药瓶	25 mg	正在检索价格...... 无法检索价格。最小订购数量为倍数 Maximum Quantity is 以订单确认为准更多信息您节约了 ()。 — Request Pricing 登录查看价格	查看库存情况 —	添加到收藏夹添加到收藏夹添加到我的收藏夹
516481-5MGCN	正在查询供货情况...... — 目前缺货有货停产少量现货供货情况有待确认登录查看库存有货目前缺货有货其余：另行通知其余：另行通知另行通知联系客户服务 Contact Customer Service 联系客户服务联系客户服务	塑胶安瓿;塑胶针药瓶	5 mg	正在检索价格...... 无法检索价格。最小订购数量为倍数 Maximum Quantity is 以订单确认为准更多信息您节约了 ()。 — Request Pricing 登录查看价格	查看库存情况 —	添加到收藏夹添加到收藏夹添加到我的收藏夹

Description
Overview	A reversible inhibitor of aspartic proteases. Inhibits cathepsin D, pepsin, and renin. Reported to block apoptosis induced by CA-074 (Cat. No. 205530) in PC12 cell lines. Also available as a 25 mM solution in DMSO (Cat. No. 508437).
Overview	Effective concentration: 1.0 µM.
Catalogue Number	516481
Brand Family	Calbiochem®
Synonyms	Iva-Val-Val-Sta-Ala-Sta, Isovaleryl-Val-Val-4-amino-3-hydroxy-6-methylheptanoyl-Ala-4-amino-3-hydroxy-6-methylheptanoic Acid

References
References	Isahara, K., et al. 1999. Neuroscience 91, 233. Kanamori, S., et al. 1998. Biochem. Biophys. Res. Commun. 251, 204. Szewczuk, Z., et al. 1992. Int. J. Pept. Prot. Res. 40, 233. Carraway, R.E., et al. 1991. Peptides 12, 107. Eid, M., et al. 1981. Biochem. J. 197, 465. Umezawa, H., et al. 1970. J. Antibiot. 23, 259.

Product Information
CAS number	26305-03-3
ATP Competitive	N
Form	White solid
Hill Formula	C₃₄H₆₃N₅O₉
Chemical formula	C₃₄H₆₃N₅O₉
Optical rotation	Optical rotation: -90.0 ± 5° (c = 0.5, MeOH, 20°C).
Reversible	Y
Quality Level	MQ100

Applications

Biological Information
Primary Target	cathepsin D
Primary Target IC<sub>50</sub>	EC50 = 1.0 µM in blocking apoptosis induced by CA-074 in PC12 cell lines
Purity	≥98% by HPLC

Physicochemical Information
Cell permeable	N

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS
RTECS	SC6155000

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Ambient Temperature Only
Toxicity	Standard Handling
Storage	+2°C to +8°C
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 4 months at -20°C.

Packaging Information

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
516481-100MGCN	04055977198812
516481-25MGCN	07790788055837
516481-5MGCN	04055977198836

Documentation

Pepstatin A, Synthetic - CAS 26305-03-3 - Calbiochem MSDS

职位
物料安全数据表 (MSDS)

Pepstatin A, Synthetic - CAS 26305-03-3 - Calbiochem 分析证书

标题	批号
516481	输入批号

参考

参考信息概述
Isahara, K., et al. 1999. Neuroscience 91, 233. Kanamori, S., et al. 1998. Biochem. Biophys. Res. Commun. 251, 204. Szewczuk, Z., et al. 1992. Int. J. Pept. Prot. Res. 40, 233. Carraway, R.E., et al. 1991. Peptides 12, 107. Eid, M., et al. 1981. Biochem. J. 197, 465. Umezawa, H., et al. 1970. J. Antibiot. 23, 259.

小册子

标题
Western Blotting Tools

技术信息

标题
Protein Blotting Handbook: 6th Edition

数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	11-October-2013 JSW
Synonyms	Iva-Val-Val-Sta-Ala-Sta, Isovaleryl-Val-Val-4-amino-3-hydroxy-6-methylheptanoyl-Ala-4-amino-3-hydroxy-6-methylheptanoic Acid
Description	A reversible inhibitor of aspartic proteases. Inhibits cathepsin D, pepsin, and renin. Reported to block apoptosis induced by CA-074 (Cat. No. 205530) in PC12 cells. Effective concentration: 1 µM.
Form	White solid
Recommended reaction conditions	Activity: Activity is measured by inhibition of pepsin. 1 U corresponds to the amount of inhibitor that reduces the activity of pepsin by 1 U (1 U of enzyme corresponds to the amount of enzyme that results in the increases the absorbance at 280 nm by 0.001 per min at pH 2.0, 37°C.)
CAS number	26305-03-3
RTECS	SC6155000
Chemical formula	C₃₄H₆₃N₅O₉
Purity	≥98% by HPLC
Solubility	DMSO (1 mg/ml) or Methanol (1 mg/ml)
Storage	+2°C to +8°C
Do Not Freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 4 months at -20°C.
Toxicity	Standard Handling
Merck USA index	14, 7147
References	Isahara, K., et al. 1999. Neuroscience 91, 233. Kanamori, S., et al. 1998. Biochem. Biophys. Res. Commun. 251, 204. Szewczuk, Z., et al. 1992. Int. J. Pept. Prot. Res. 40, 233. Carraway, R.E., et al. 1991. Peptides 12, 107. Eid, M., et al. 1981. Biochem. J. 197, 465. Umezawa, H., et al. 1970. J. Antibiot. 23, 259.

种类

Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Proteases Inhibitors

此产品已添加到您的购物车。