520222 Sigma-AldrichPPACK, Dihydrochloride - CAS 82188-90-7 - Calbiochem
PPACK, Dihydrochloride, CAS 142036-63-3, is a highly potent, selective & irreversible inhibitor of thrombin. Reacts with thrombin in a 1:1 stoichiometry. Can also inhibit tPA, Factors VIIa & XIa.
More>> PPACK, Dihydrochloride, CAS 142036-63-3, is a highly potent, selective & irreversible inhibitor of thrombin. Reacts with thrombin in a 1:1 stoichiometry. Can also inhibit tPA, Factors VIIa & XIa. Less<<MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
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概述
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重要规格表
| CAS # | Empirical Formula |
|---|---|
| 82188-90-7 | C₂₁H₃₃N₆O₃•2HCl |
价格及供货情况
| 产品目录编号 | 库存情况 | 包装 | 数量 / 包装 | 价格 | 数量 | |
|---|---|---|---|---|---|---|
| 520222-25MGCN |
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塑胶安瓿;塑胶针药瓶 | 25 mg |
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| 520222-5MGCN |
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塑胶安瓿;塑胶针药瓶 | 5 mg |
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— |
| Description | |
|---|---|
| Overview | Extremely potent and selective irreversible inhibitor of thrombin (Kobs/[I] = 107M-1S-1). Reacts with thrombin in a 1:1 stoichiometry. Can also be used to inhibit tissue plasminogen activator, Factor VIIa, and Factor XIa. Also available as a 25 mM solution in H2O (Cat. No. 508773). |
| Catalogue Number | 520222 |
| Brand Family | Calbiochem® |
| Product Information | |
|---|---|
| CAS number | 82188-90-7 |
| ATP Competitive | N |
| Form | White solid |
| Hill Formula | C₂₁H₃₃N₆O₃•2HCl |
| Chemical formula | C₂₁H₃₃N₆O₃•2HCl |
| Hygroscopic | Hygroscopic |
| Reversible | N |
| Quality Level | MQ100 |
| Biological Information | |
|---|---|
| Primary Target | Thrombin |
| Primary Target IC<sub>50</sub> | Kobs/[I] = 107 M⁻¹ sec⁻¹ as inhibitor of thrombin |
| Purity | ≥80% by HPLC |
| Physicochemical Information | |
|---|---|
| Cell permeable | N |
| Peptide Sequence | H-D-Phe-Pro-Arg-chloromethylketone, 2HCl |
| Dimensions |
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| Materials Information |
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| Toxicological Information |
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| Safety Information according to GHS |
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| Safety Information |
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| Product Usage Statements |
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| Packaging Information | |
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| Packaged under inert gas | Packaged under inert gas |
| Transport Information |
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| Supplemental Information |
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| Specifications |
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| Global Trade Item Number | |
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| 产品目录编号 | GTIN |
| 520222-25MGCN | 04055977271294 |
| 520222-5MGCN | 07790788051020 |
Documentation
PPACK, Dihydrochloride - CAS 82188-90-7 - Calbiochem MSDS
| 职位 |
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PPACK, Dihydrochloride - CAS 82188-90-7 - Calbiochem 分析证书
| 标题 | 批号 |
|---|---|
| 520222 |
参考
| 参考信息概述 |
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| Rosado, J. A., et al. 2002. J. Biol. Chem. 277, 42157. Odake S., et al. 1995. J. Enzyme Inhib. 9, 17. Arni, R.K., et al. 1993. Biochemistry 32, 4727. Yamashita, T., et al. 1993. Thromb. Res. 69, 93. Schmaier, A.H., et al. 1992. Thromb. Res. 67, 479. Collen, D., et al. 1982. J. Lab. Clin. Med. 99, 76. Kettner, C., and Shaw, E. 1981. Methods Enzymol. 80, 826. Kettner, C., and Shaw, E. 1979. Thromb. Res. 14, 969. |
引用
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Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
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