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			96-Well Plate

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	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

370654 Sigma-AldrichPKG Inhibitor - Calbiochem

The PKG Inhibitor controls the biological activity of PKG. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

PKG Inhibitor - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书
参考
Data Sheet

同义词: Protein Kinase G Inhibitor, RKRARKE

Primary Target: PKG

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概述

Replacement Information

重要规格表

Empirical Formula
C₃₈H₇₄N₁₈O₁₀

价格及供货情况

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Description
Overview	A more specific, reversible, and substrate competitive inhibitor of protein kinase G (K_i = 86 µM) relative to protein kinase A (K_i = 550 µM). Sequence corresponds to a non-phosphorylatable analog (Ser³² to Ala³²) of histone H2B (amino acids 29-35).
Catalogue Number	370654
Brand Family	Calbiochem®
Synonyms	Protein Kinase G Inhibitor, RKRARKE

References
References	Glass, D.B., et al. 1983. Biochem. J. 213, 159.

Product Information
ATP Competitive	N
Form	Lyophilized
Hill Formula	C₃₈H₇₄N₁₈O₁₀
Chemical formula	C₃₈H₇₄N₁₈O₁₀
Hygroscopic	Hygroscopic
Reversible	Y
Sold on the basis of peptide content	Y
Quality Level	MQ100

Applications

Biological Information
Primary Target	PKG
Primary Target K<sub>i</sub>	86 µM against protein kinase G
Purity	≥95% by HPLC

Physicochemical Information
Cell permeable	N
Peptide Content	Y
Peptide Sequence	H-Arg-Lys-Arg-Ala-Arg-Lys-Glu-OH

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Ambient Temperature Only
Toxicity	Standard Handling
Storage	-20°C
Hygroscopic	Hygroscopic
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.

Packaging Information

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
370654-1MGCN	04055977191646

Documentation

PKG Inhibitor - Calbiochem MSDS

职位
物料安全数据表 (MSDS)

PKG Inhibitor - Calbiochem 分析证书

标题	批号
370654	输入批号

参考

参考信息概述
Glass, D.B., et al. 1983. Biochem. J. 213, 159.

数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	11-January-2010 RFH
Synonyms	Protein Kinase G Inhibitor, RKRARKE
Description	A specific, reversible, and substrate competitive inhibitor of PKG (K_i = 86 µM) relative to PKA (K_i = 550 µM). Sequence corresponds to a non-phosphorylatable analog (Ser³² to Ala³²) of histone H2B (amino acids 29-35).
Form	Lyophilized
Chemical formula	C₃₈H₇₄N₁₈O₁₀
Peptide Sequence	H-Arg-Lys-Arg-Ala-Arg-Lys-Glu-OH
Purity	≥95% by HPLC
Solubility	H₂O (1 mg/ml)
Storage	-20°C Hygroscopic
Do Not Freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.
Toxicity	Standard Handling
References	Glass, D.B., et al. 1983. Biochem. J. 213, 159.

种类

Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Protein Phosphorylation / Dephosphorylation > Protein Kinase G (PKG; cGMP-Dependent Protein Kinase) Inhibitors

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