Millipore Sigma Vibrant Logo

476485 PKA Inhibitor 14-22 Amide, Cell-Permeable, Myristoylated - Calbiochem

PKA Inhibitor 14-22 Amide is myristoylated at the N-terminus that enhances its cell-permeability. The non-myristoylated version is shown to be a specific inhibitor of PKA (Ki = 36 nM).

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

同义词: PKI 14-22 Amide, Cell-Permeable, Myr-GRTGRRNAI-NH₂, Myristoylated Protein Kinase A Inhibitor Amide 14-22, Cell-Permeable, Protein Kinase A Inhibitor 14-22 Amide, PKA Inhibitor XIII

Primary Target: cAMP-dependent protein kinase
View Products on Sigmaaldrich.com
476485
查看价格及供货情况

概述

Replacement Information

重要规格表

Empirical Formula
C₅₃H₁₀₀N₂₀O₁₂

价格及供货情况

产品目录编号 库存情况包装 数量 / 包装 价格 数量
476485-500UGCN
正在查询供货情况......
—
目前缺货 目前缺货
有货 
停产
少量现货
供货情况有待确认
    其余：另行通知
      其余：另行通知
      另行通知
      联系客户服务
      Contact Customer Service

      		 塑胶安瓿;塑胶针药瓶 500 μg
      正在检索价格......
      无法检索价格。
      最小订购数量为倍数
      Maximum Quantity is
      以订单确认为准 更多信息
      您节约了 ()。
       
      —
      Request Pricing
      		 —
      Description
      OverviewHeat-stable protein kinase inhibitor (PKI) peptide sequence (14 - 22) that has been myristoylated at the N-terminus, enhancing its cell-permeability. The non-myristoylated version of this peptide is a highly specific inhibitor (Ki = 36 nM) of cAMP-dependent protein kinase.
      Catalogue Number476485
      Brand Family Calbiochem®
      SynonymsPKI 14-22 Amide, Cell-Permeable, Myr-GRTGRRNAI-NH₂, Myristoylated Protein Kinase A Inhibitor Amide 14-22, Cell-Permeable, Protein Kinase A Inhibitor 14-22 Amide, PKA Inhibitor XIII
      References
      ReferencesPaman, K., et al. 1998. J. Lipid Res. 39, 1091.
      Rimon, G., and Rubin M. 1998. Biochim. Biophys. Acta 1380, 289.
      Harris, T.E., et al. 1997. Biochem. Biophys. Res. Commun. 232, 648.
      Muniz, M., et al. 1997. Proc. Natl. Acad. Sci. USA 94, 14461.
      Zoukhri, D., et al. 1997. Am. J. Physiol. 272, C263.
      Eichholtz, T., et al. 1993. J. Biol. Chem. 268, 1982.
      Ward, N.E. and O’Brian, C.A. 1993. Biochemistry 32, 11903.
      Walsh, D.A. and Glass, D.B. 1991. Methods Enzymol. 201, 304.
      Glass, D.B., et al. 1989. J. Biol. Chem. 264, 8802.
      Product Information
      ATP CompetitiveN
      FormLyophilized
      FormulationSupplied as a trifluoroacetate salt.
      Hill FormulaC₅₃H₁₀₀N₂₀O₁₂
      Chemical formulaC₅₃H₁₀₀N₂₀O₁₂
      Hygroscopic Hygroscopic
      ReversibleN
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetcAMP-dependent protein kinase
      Primary Target K<sub>i</sub>36 nMf or cAMP-dependent protein kinase
      Purity≥95% by HPLC
      Physicochemical Information
      Cell permeableY
      Peptide SequenceMyr-N-Gly-Arg-Thr-Gly-Arg-Arg-Asn-Ala-Ile-NH₂
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      产品目录编号 GTIN
      476485-500UGCN 04055977183832

      Documentation

      PKA Inhibitor 14-22 Amide, Cell-Permeable, Myristoylated - Calbiochem MSDS

      职位

      物料安全数据表 (MSDS) 

      PKA Inhibitor 14-22 Amide, Cell-Permeable, Myristoylated - Calbiochem 分析证书

      标题批号
      476485

      参考

      参考信息概述
      Paman, K., et al. 1998. J. Lipid Res. 39, 1091.
      Rimon, G., and Rubin M. 1998. Biochim. Biophys. Acta 1380, 289.
      Harris, T.E., et al. 1997. Biochem. Biophys. Res. Commun. 232, 648.
      Muniz, M., et al. 1997. Proc. Natl. Acad. Sci. USA 94, 14461.
      Zoukhri, D., et al. 1997. Am. J. Physiol. 272, C263.
      Eichholtz, T., et al. 1993. J. Biol. Chem. 268, 1982.
      Ward, N.E. and O’Brian, C.A. 1993. Biochemistry 32, 11903.
      Walsh, D.A. and Glass, D.B. 1991. Methods Enzymol. 201, 304.
      Glass, D.B., et al. 1989. J. Biol. Chem. 264, 8802.
      数据表

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision11-August-2008 RFH
      SynonymsPKI 14-22 Amide, Cell-Permeable, Myr-GRTGRRNAI-NH₂, Myristoylated Protein Kinase A Inhibitor Amide 14-22, Cell-Permeable, Protein Kinase A Inhibitor 14-22 Amide, PKA Inhibitor XIII
      DescriptionHeat-stable protein kinase inhibitor (PKI) peptide sequence (14-22) that has been myristoylated at the N-terminus, enhancing its cell-permeability. The non-myristoylated version of this peptide is a highly specific inhibitor (Ki = 36 nM) of cAMP-dependent protein kinase (PKA).
      FormLyophilized
      FormulationSupplied as a trifluoroacetate salt.
      Chemical formulaC₅₃H₁₀₀N₂₀O₁₂
      Peptide SequenceMyr-N-Gly-Arg-Thr-Gly-Arg-Arg-Asn-Ala-Ile-NH₂
      Purity≥95% by HPLC
      SolubilityH₂O (1 mg/ml)
      Storage -20°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesPaman, K., et al. 1998. J. Lipid Res. 39, 1091.
      Rimon, G., and Rubin M. 1998. Biochim. Biophys. Acta 1380, 289.
      Harris, T.E., et al. 1997. Biochem. Biophys. Res. Commun. 232, 648.
      Muniz, M., et al. 1997. Proc. Natl. Acad. Sci. USA 94, 14461.
      Zoukhri, D., et al. 1997. Am. J. Physiol. 272, C263.
      Eichholtz, T., et al. 1993. J. Biol. Chem. 268, 1982.
      Ward, N.E. and O’Brian, C.A. 1993. Biochemistry 32, 11903.
      Walsh, D.A. and Glass, D.B. 1991. Methods Enzymol. 201, 304.
      Glass, D.B., et al. 1989. J. Biol. Chem. 264, 8802.