Optiseal–M Cartridge Filters with Hydrophobic Aervent Membrane
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概述
规格
订货信息
Documentation
相关产品和应用
产品族
Optiseal Cartridge Filters with Hydrophobic Aervent MembraneOptiseal filters with Aervent membrane are designed for sterilizing applications, removing particles and microorganisms from gases and solvents.详细了解 >> |
Aervent–50 Disposable Filters with Hydrophobic Aervent MembraneThis sterilizing-grade filter is designed for critical small scale gas line and air venting applications.详细了解 >> |
相关产品，按下列排序： Application Facete
| Sterility Testing |
| Fermentation Solutions |
| Dialysis and Filtration |
相关产品，按下列排序： Brand Facete
| Optiseal® |
种类
| Biopharmaceutical Manufacturing > Downstream Processing > Sterile Filtration > Sterile Gas > Aervent |
Description
Optiseal-M filters with Aervent membrane are 0.2 µm hydrophobic cartridges. They are designed for sterilizing applications, removing particles and microorganisms from gases and solvents. They are made with PTFE membrane and polypropylene components for broad application compatibility. Optiseal-M filters with Aervent membrane are designed to be used with Millidisk housings.
Each unit is 100% integrity tested during manufacturing to guarantee integrity.
Typical Applications
The sterilizing grade rating is based on ASTM liquid bacterial retention challenge. In gases this filter will remove contamination down to 0.01 µm. Optiseal-M Aervent hydrophobic cartridges will remove particles and microorganisms from gases and liquids for low flow rates.
- Sterile tank venting
- Fermentation air applications
- Bioreactor inlet and outlet filtration
- Autoclaves
- Sterile process gases
Cartridges will also sterilize alcohol streams.
| Materials of Construction | ||
| Filter | Polytetrafluoroethylene (PTFE) | |
| Supports | Polypropylene | |
| O-ring | Silicone (SI) | |
| Connections | Not Applicable | |
| Filtration Area | 0.05 m² | |
| Maximum Differential Pressure, bar (psid) | Forward: 5.5 bar (80 psid) @ 25 °C; 1.7 bar (25 psid) @ 80 °C; 0.35 bar (5 psid) @ 135 °C. Reverse: 4.1 bar (60 psid) | |
| Bacterial Retention | Samples were quantitatively retentive of a minimum Brevundimonas diminuta challenge concentration of 1 x 10⁷ CFU/cm² using ASTM® F838 methodology. | |
| Bacterial Endotoxins | Aqueous extraction contains ≤0.5 EU/mL as determined by the Limulus Amebocyte Lysate (LAL) Test | |
| Toxicity | Component materials meet the requirements of the USP Class VI Biological Test for Plastics. The cartridges also meet the requirements of the USP General (Mouse) Safety Test. | |
| Sterilization | 80 (40 forward/40 reverse) SIP cycles of 30 min @ 135 °C | |
| Integrity Test | ||
| Bubble Point | ≥1100 mbar (16 psig) nitrogen with 70/30 % IPA/water | |