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496100 Sigma-AldrichOmeprazole - CAS 73590-58-6 - Calbiochem

A cell-permeable pyridyl methylsulfinyl benzimidazole compound that acts as selective proton pump inhibitor.

Omeprazole - CAS 73590-58-6 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书
参考
Data Sheet

同义词: H 168/68, 5-Methoxy-2[(4-methoxy-3,5-dimethyl-2-pyridyl)methylsulfinyl]-1H-benzimidazole

Primary Target: proton pump

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概述

Replacement Information

重要规格表

CAS #	Empirical Formula
73590-58-6	C₁₇H₁₉N₃O₃S

价格及供货情况

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Description
Overview	A cell-permeable pyridyl methylsulfinyl benzimidazole compound that acts as selective proton pump inhibitor. Behaves as a prodrug by undergoing an acid-catalyzed rearrangement to a thiol-reactive cationic sulfenamide that inhibits (H⁺, K⁺)-ATPase in the gastric milieu. An aryl hydrocarbon-like inducer of cytochrome P450 secretion in human liver.
Catalogue Number	496100
Brand Family	Calbiochem®
Synonyms	H 168/68, 5-Methoxy-2[(4-methoxy-3,5-dimethyl-2-pyridyl)methylsulfinyl]-1H-benzimidazole

References
References	Lambrecht, N., et al. 2000. J. Biol. Chem. 275, 4041. Besancon, M., et al. 1997. J. Biol. Chem. 272, 22438. Sachs, G., et al. 1995. Ann. Rev. Pharmacol. Toxicol. 35, 277. Diaz, D., et al. 1990. Gastroenterology 99, 737. Fellenius, E., et al. 1981. Nature 290, 159.

Product Information
CAS number	73590-58-6
ATP Competitive	N
Form	Tan to off-white solid
Hill Formula	C₁₇H₁₉N₃O₃S
Chemical formula	C₁₇H₁₉N₃O₃S
Reversible	N
Structure formula Image
Quality Level	MQ100

Applications

Biological Information
Primary Target	proton pump
Purity	≥94% by HPLC

Physicochemical Information
Cell permeable	Y
Contaminants	Heavy metals: ≤20 ppm

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS
RTECS	DD9087000

Safety Information
R Phrase	R: 36/37/38 Irritating to eyes, respiratory system and skin.
S Phrase	S: 26-36 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing.

Product Usage Statements

Storage and Shipping Information
Ship Code	Ambient Temperature Only
Toxicity	Irritant
Storage	+2°C to +8°C
Protect from Light	Protect from light
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Packaging Information
Packaged under inert gas	Packaged under inert gas

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
496100-50MGCN	04055977199833

Documentation

Omeprazole - CAS 73590-58-6 - Calbiochem MSDS

职位
物料安全数据表 (MSDS)

Omeprazole - CAS 73590-58-6 - Calbiochem 分析证书

标题	批号
496100	输入批号

参考

参考信息概述
Lambrecht, N., et al. 2000. J. Biol. Chem. 275, 4041. Besancon, M., et al. 1997. J. Biol. Chem. 272, 22438. Sachs, G., et al. 1995. Ann. Rev. Pharmacol. Toxicol. 35, 277. Diaz, D., et al. 1990. Gastroenterology 99, 737. Fellenius, E., et al. 1981. Nature 290, 159.

数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	13-March-2013 JSW
Synonyms	H 168/68, 5-Methoxy-2[(4-methoxy-3,5-dimethyl-2-pyridyl)methylsulfinyl]-1H-benzimidazole
Description	A cell-permeable, selective proton pump inhibitor. Behaves as a prodrug by undergoing an acid-catalyzed rearrangement to a thiol-reactive cationic sulfenamide that inhibits (H⁺-K⁺)-ATPase in the gastric milieu. Also acts as an aryl hydrocarbon-like inducer of cytochrome P450 secretion in human liver.
Form	Tan to off-white solid
Intert gas (Yes/No)	Packaged under inert gas
CAS number	73590-58-6
RTECS	DD9087000
Chemical formula	C₁₇H₁₉N₃O₃S
Structure formula
Purity	≥94% by HPLC
Contaminants	Heavy metals: ≤20 ppm
Solubility	DMSO (25 mg/ml)
Storage	Protect from light +2°C to +8°C
Do Not Freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity	Irritant
Merck USA index	14, 6845
References	Lambrecht, N., et al. 2000. J. Biol. Chem. 275, 4041. Besancon, M., et al. 1997. J. Biol. Chem. 272, 22438. Sachs, G., et al. 1995. Ann. Rev. Pharmacol. Toxicol. 35, 277. Diaz, D., et al. 1990. Gastroenterology 99, 737. Fellenius, E., et al. 1981. Nature 290, 159.

种类

Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > ATPase/GTPase Inhibitors > ATPase Inhibitors

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