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483125 Sigma-AldrichN^G-Nitro-L-arginine Methyl Ester, Hydrochloride - CAS 51298-62-5 - Calbiochem

Cell permeable. More soluble analog of arginine and a competitive, slowly reversible inhibitor of eNOS (IC₅₀ = 500 nM). Causes a prolonged inhibition of acetylcholine-induced relaxation of rat aortic rings (IC₅₀ = 400 nM).

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书
参考
小册子
Data Sheet

同义词: N^ω-NO₂-L-Arg-OMe, N^G-NO₂-L-Arg-OMe, L-NAME, HCl

Primary Target: eNOS

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概述

Replacement Information

重要规格表

CAS #	Empirical Formula
51298-62-5	C₇H₁₅N₅O₄ . HCl

价格及供货情况

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Description
Overview	Cell permeable. More soluble analog of arginine and a competitive, slowly reversible inhibitor of eNOS (IC₅₀ = 500 nM). Causes a prolonged inhibition of acetylcholine-induced relaxation of rat aortic rings (IC₅₀ = 400 nM).
Catalogue Number	483125
Brand Family	Calbiochem®
Synonyms	N^ω-NO₂-L-Arg-OMe, N^G-NO₂-L-Arg-OMe, L-NAME, HCl

References
References	Baylis, C., et al. 1995. J. Pharmacol. Exp. Ther. 274, 1135. Dawson, V.L., et al. 1991. Proc. Natl. Acad. Sci. USA 88, 6368. Kubes, P., et al. 1991. Proc. Natl. Acad. Sci. USA 88, 4651. Moncada, S., et al. 1991. Pharmacol. Rev. 43, 109. Moore, P.K., et al. 1990. Br. J. Pharmacol. 99, 408.

Product Information
CAS number	51298-62-5
ATP Competitive	N
Form	White to off-white solid
Hill Formula	C₇H₁₅N₅O₄ . HCl
Chemical formula	C₇H₁₅N₅O₄ . HCl
Hygroscopic	Hygroscopic
Reversible	Y
Structure formula Image
Quality Level	MQ100

Applications

Biological Information
Primary Target	eNOS
Primary Target IC<sub>50</sub>	500 nM against eNOS
Purity	≥98% by HPLC

Physicochemical Information
Cell permeable	Y

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Blue Ice Only
Toxicity	Standard Handling
Storage	-20°C
Protect from Light	Protect from light
Hygroscopic	Hygroscopic
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 4 months at -20°C.

Packaging Information
Packaged under inert gas	Packaged under inert gas

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
483125-100MGCN	04055977200652

Documentation

N^G-Nitro-L-arginine Methyl Ester, Hydrochloride - CAS 51298-62-5 - Calbiochem MSDS

职位
物料安全数据表 (MSDS)

N^G-Nitro-L-arginine Methyl Ester, Hydrochloride - CAS 51298-62-5 - Calbiochem 分析证书

标题	批号
483125	输入批号

参考

参考信息概述
Baylis, C., et al. 1995. J. Pharmacol. Exp. Ther. 274, 1135. Dawson, V.L., et al. 1991. Proc. Natl. Acad. Sci. USA 88, 6368. Kubes, P., et al. 1991. Proc. Natl. Acad. Sci. USA 88, 4651. Moncada, S., et al. 1991. Pharmacol. Rev. 43, 109. Moore, P.K., et al. 1990. Br. J. Pharmacol. 99, 408.

小册子

标题
Pathways and Biomarkers of Oxidative Stress

数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	29-November-2010 RFH
Synonyms	N^ω-NO₂-L-Arg-OMe, N^G-NO₂-L-Arg-OMe, L-NAME, HCl
Description	More soluble analog of arginine and a competitive, slowly reversible inhibitor of endothelial nitric oxide synthase (IC₅₀ = 500 nM). Causes a prolonged inhibition of acetylcholine-induced relaxation of rat aortic rings (IC₅₀ = 400 nM).
Form	White to off-white solid
Intert gas (Yes/No)	Packaged under inert gas
CAS number	51298-62-5
Chemical formula	C₇H₁₅N₅O₄ . HCl
Structure formula
Purity	≥98% by HPLC
Solubility	H₂O (50 mg/ml)
Storage	Protect from light -20°C Hygroscopic
Do Not Freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 4 months at -20°C.
Toxicity	Standard Handling
References	Baylis, C., et al. 1995. J. Pharmacol. Exp. Ther. 274, 1135. Dawson, V.L., et al. 1991. Proc. Natl. Acad. Sci. USA 88, 6368. Kubes, P., et al. 1991. Proc. Natl. Acad. Sci. USA 88, 4651. Moncada, S., et al. 1991. Pharmacol. Rev. 43, 109. Moore, P.K., et al. 1990. Br. J. Pharmacol. 99, 408.

种类

Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Nitric Oxide and Oxidative Stress > Nitric Oxide Synthase (NOS) Inhibitors

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483125 Sigma-AldrichN^G-Nitro-L-arginine Methyl Ester, Hydrochloride - CAS 51298-62-5 - Calbiochem

Cell permeable. More soluble analog of arginine and a competitive, slowly reversible inhibitor of eNOS (IC₅₀ = 500 nM). Causes a prolonged inhibition of acetylcholine-induced relaxation of rat aortic rings (IC₅₀ = 400 nM).

同义词: N^ω-NO₂-L-Arg-OMe, N^G-NO₂-L-Arg-OMe, L-NAME, HCl

Recommended Products

概述

重要规格表

价格及供货情况

Documentation

N^G-Nitro-L-arginine Methyl Ester, Hydrochloride - CAS 51298-62-5 - Calbiochem MSDS

N^G-Nitro-L-arginine Methyl Ester, Hydrochloride - CAS 51298-62-5 - Calbiochem 分析证书

参考

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Cell permeable. More soluble analog of arginine and a competitive, slowly reversible inhibitor of eNOS (IC₅₀ = 500 nM). Causes a prolonged inhibition of acetylcholine-induced relaxation of rat aortic rings (IC₅₀ = 400 nM).

同义词: Nω-NO₂-L-Arg-OMe, NG-NO₂-L-Arg-OMe, L-NAME, HCl

Recommended Products

重要规格表

价格及供货情况

NG-Nitro-L-arginine Methyl Ester, Hydrochloride - CAS 51298-62-5 - Calbiochem MSDS

NG-Nitro-L-arginine Methyl Ester, Hydrochloride - CAS 51298-62-5 - Calbiochem 分析证书

参考

小册子

种类

最近查看的内容

同义词: N^ω-NO₂-L-Arg-OMe, N^G-NO₂-L-Arg-OMe, L-NAME, HCl

N^G-Nitro-L-arginine Methyl Ester, Hydrochloride - CAS 51298-62-5 - Calbiochem MSDS

N^G-Nitro-L-arginine Methyl Ester, Hydrochloride - CAS 51298-62-5 - Calbiochem 分析证书