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Most commonly-used free radical trap. An antioxidant that has been shown to act as a protective agent in several experimental models of neurodegenerative disorders. Inhibits lipid peroxidation in rat liver microsomes. Also prevents the induction of inducible nitric oxide synthase (iNOS) by reactive oxygen species.
Catalogue Number
203995
Brand Family
Calbiochem®
Synonyms
PBN
References
References
Floyd, R.A. 1997. Adv. Pharmacol. 38, 361. Miyajima, T., and Kotake, Y. 1995. Biochem. Biophys. Res. Commun. 215, 114. Jazen, E.G., et al. 1994. in Frontiers of Reactive Oxygen Species in Biology and Medicine, (Asada, K., and Yoshikawa, T., eds.), pp. 431-434. Elsevier Science, Amsterdam. Floyd, R.A. 1990. FASEB J. 4, 2587.
Following reconstitution in DMSO aliquot and freeze (-20°C). Stock solutions in DMSO are stable for up to 2 months at -20°C. Unstable in aqueous solution; reconstitute just prior to use.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
产品目录编号
GTIN
203995-500MGCN
04055977220018
Documentation
N-tert-Butyl-α-phenylnitrone - CAS 3376-24-7 - Calbiochem MSDS
N-tert-Butyl-α-phenylnitrone - CAS 3376-24-7 - Calbiochem 分析证书
标题
批号
203995
参考
参考信息概述
Floyd, R.A. 1997. Adv. Pharmacol. 38, 361. Miyajima, T., and Kotake, Y. 1995. Biochem. Biophys. Res. Commun. 215, 114. Jazen, E.G., et al. 1994. in Frontiers of Reactive Oxygen Species in Biology and Medicine, (Asada, K., and Yoshikawa, T., eds.), pp. 431-434. Elsevier Science, Amsterdam. Floyd, R.A. 1990. FASEB J. 4, 2587.
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
Revision
22-May-2008 RFH
Synonyms
PBN
Description
Most commonly used free radical trap. An antioxidant that has been shown to act as a protective agent in several experimental models of neurodegenerative diseases. Inhibits lipid peroxidation in rat liver microsomes. Also prevents the induction of inducible nitric oxide synthase (iNOS) by reactive oxygen species.
Form
White solid
CAS number
3376-24-7
Chemical formula
C₁₁H₁₅NO
Structure formula
Purity
≥98% by GC
Solubility
DMSO (10 mg/ml), H₂O (20 mg/ml), or Chloroform (50 mg/ml)
Storage
-20°C
Do Not Freeze
Ok to freeze
Special Instructions
Following reconstitution in DMSO aliquot and freeze (-20°C). Stock solutions in DMSO are stable for up to 2 months at -20°C. Unstable in aqueous solution; reconstitute just prior to use.
Toxicity
Standard Handling
References
Floyd, R.A. 1997. Adv. Pharmacol. 38, 361. Miyajima, T., and Kotake, Y. 1995. Biochem. Biophys. Res. Commun. 215, 114. Jazen, E.G., et al. 1994. in Frontiers of Reactive Oxygen Species in Biology and Medicine, (Asada, K., and Yoshikawa, T., eds.), pp. 431-434. Elsevier Science, Amsterdam. Floyd, R.A. 1990. FASEB J. 4, 2587.
