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475913
Sigma-AldrichMycophenolic Acid - CAS 24280-93-1 - Calbiochem
An immunosuppressive agent that inhibits de novo purine nucleotide synthesis via inhibition of inosine monophosphate dehydrogenase and prevents the formation of XMP and GMP.
More>>An immunosuppressive agent that inhibits de novo purine nucleotide synthesis via inhibition of inosine monophosphate dehydrogenase and prevents the formation of XMP and GMP. Less<<
MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
An immunosuppressive agent that inhibits de novo purine nucleotide synthesis via inhibition of inosine monophosphate dehydrogenase and prevents the formation of XMP and GMP. Useful for selection of animal cells that express the E. coli gene coding for xanthine-guanine phosphoribosyltransferase. Also suppresses cytokine-induced nitric oxide production in mouse and rat vascular endothelial cells.
Langman, L.J., et al. 1995. Clin. Chem. 41, 295. Senda, M., et al. 1995. Transplantation60, 1143. Warner-Bartnicki, A.L., et al. 1993. Exp. Cell Res.204, 241. Falkner, F.G., and Moss, B. 1988. J. Virol.62, 1849. Cohen, M.B., et al. 1981. J. Biol. Chem.256, 8713. Mulligan, R.C., and Berg, P. 1981. Proc. Natl. Acad. Sci. USA78, 2072.
Harmful by inhalation, in contact with skin and if swallowed. Limited evidence of a carcinogenic effect.
S Phrase
S: 22-36
Do not breathe dust. Wear suitable protective clothing.
Product Usage Statements
Storage and Shipping Information
Ship Code
Ambient Temperature Only
Toxicity
Harmful & Carcinogenic / Teratogenic
Storage
+15°C to +30°C
Do not freeze
Ok to freeze
Special Instructions
Following reconstitution, sterilize by filtration through a 0.22 µm pore-size filter, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
产品目录编号
GTIN
475913-100MGCN
04055977184822
475913-500MGCN
04055977184150
Documentation
Mycophenolic Acid - CAS 24280-93-1 - Calbiochem MSDS
Mycophenolic Acid - CAS 24280-93-1 - Calbiochem 分析证书
标题
批号
475913
参考
参考信息概述
Langman, L.J., et al. 1995. Clin. Chem. 41, 295. Senda, M., et al. 1995. Transplantation60, 1143. Warner-Bartnicki, A.L., et al. 1993. Exp. Cell Res.204, 241. Falkner, F.G., and Moss, B. 1988. J. Virol.62, 1849. Cohen, M.B., et al. 1981. J. Biol. Chem.256, 8713. Mulligan, R.C., and Berg, P. 1981. Proc. Natl. Acad. Sci. USA78, 2072.
数据表
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
An immunosuppressive agent that inhibits de novo purine nucleotide synthesis via inhibition of IMP dehydrogenase and prevents the formation of XMP and GMP. Useful for selection of animal cells that express the E. coli gene coding for xanthine-guanine phosphoribosyltransferase. Also suppresses cytokine-induced nitric oxide production in mouse and rat vascular endothelial cells.
Form
White to off-white solid
CAS number
24280-93-1
RTECS
MP8050000
Chemical formula
C₁₇H₂₀O₆
Structure formula
Purity
≥95% by HPLC
Solubility
Ethanol or 100 mM NaOH (10 mg/ml)
Storage
+15°C to +30°C
Do Not Freeze
Ok to freeze
Special Instructions
Following reconstitution, sterilize by filtration through a 0.22 µm pore-size filter, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
Toxicity
Harmful & Carcinogenic / Teratogenic
Merck USA index
14 6327
References
Langman, L.J., et al. 1995. Clin. Chem. 41, 295. Senda, M., et al. 1995. Transplantation60, 1143. Warner-Bartnicki, A.L., et al. 1993. Exp. Cell Res.204, 241. Falkner, F.G., and Moss, B. 1988. J. Virol.62, 1849. Cohen, M.B., et al. 1981. J. Biol. Chem.256, 8713. Mulligan, R.C., and Berg, P. 1981. Proc. Natl. Acad. Sci. USA78, 2072.
