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			96-Well Plate

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	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

474705 Sigma-AldrichMevastatin, Sodium Salt - Calbiochem

Carboxylate form of Mevastatin that is active in whole cells and in cell-free assays.

Mevastatin, Sodium Salt - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书
参考
Data Sheet

Primary Target: HMG-CoA reductase

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概述

Replacement Information

重要规格表

Empirical Formula
C₂₃H₃₅O₆ · Na

价格及供货情况

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Description
Overview	Carboxylate form of Mevastatin (Cat. No. 474700) that is active in whole cells and in cell-free assays.
Catalogue Number	474705
Brand Family	Calbiochem®

References
References	Sugiyama, M., et al. 2000. Biochem. Biophys. Res. Commun. 271, 88. Endo, A. 1992. J. Lipid Res. 33, 1569.

Product Information
ATP Competitive	N
Form	White to off-white solid
Hill Formula	C₂₃H₃₅O₆ · Na
Chemical formula	C₂₃H₃₅O₆ · Na
Hygroscopic	Hygroscopic
Reversible	N
Structure formula Image
Quality Level	MQ200

Applications

Biological Information
Primary Target	HMG-CoA reductase
Purity	≥98% by HPLC

Physicochemical Information
Cell permeable	N

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Ambient Temperature Only
Toxicity	Standard Handling
Storage	-20°C
Hygroscopic	Hygroscopic
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Packaging Information
Packaged under inert gas	Packaged under inert gas

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
474705-5MGCN	04055977185423

Documentation

Mevastatin, Sodium Salt - Calbiochem MSDS

职位
物料安全数据表 (MSDS)

Mevastatin, Sodium Salt - Calbiochem 分析证书

标题	批号
474705	输入批号

参考

参考信息概述
Sugiyama, M., et al. 2000. Biochem. Biophys. Res. Commun. 271, 88. Endo, A. 1992. J. Lipid Res. 33, 1569.

数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	16-September-2020 JSW
Description	Carboxylate form of Mevastatin (Cat. No. 474700) that is active in whole cells and in cell-free assays. Mevastatin is an antibiotic that acts as a potent inhibitor of HMG-CoA reductase. Suppresses Ras farnesylation and inhibits myoblast fusion. Causes cell cycle arrest in late G₁ phase. Mevastatin may also induce bone morphogenic protein-2 (BMP-2).
Form	White to off-white solid
Intert gas (Yes/No)	Packaged under inert gas
Chemical formula	C₂₃H₃₅O₆ · Na
Structure formula
Purity	≥98% by HPLC
Solubility	DMSO (30 mg/ml) or Ethanol (20 mg/ml)
Storage	-20°C Hygroscopic
Do Not Freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity	Standard Handling
References	Sugiyama, M., et al. 2000. Biochem. Biophys. Res. Commun. 271, 88. Endo, A. 1992. J. Lipid Res. 33, 1569.

种类

Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Lipid Signaling Inhibitors > HMG-CoA (3-Hydroxy-3-Methylglutaryl Coenzyme A) Reductase Inhibitors

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