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444241 Sigma-AldrichMMP-2/MMP-9 Inhibitor I - CAS 193807-58-8 - Calbiochem

The MMP-2/MMP-9 Inhibitor I, also referenced under CAS 193807-58-8, controls the biological activity of MMP-2/MMP-9. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书
参考
Data Sheet

同义词: (2R)-2-[(4-Biphenylylsulfonyl)amino]-3-phenylpropionic Acid

Primary Target: MMP-2, MMP-9

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概述

Replacement Information

重要规格表

CAS #	Empirical Formula
193807-58-8	C₂₁H₁₉NO₄S

价格及供货情况

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Description
Overview	A potent inhibitor of MMP-2 (IC₅₀ = 310 nM) and MMP-9 (IC₅₀ = 240 nM). Orally active in animal models of tumor growth and metastasis.
Catalogue Number	444241
Brand Family	Calbiochem®
Synonyms	(2R)-2-[(4-Biphenylylsulfonyl)amino]-3-phenylpropionic Acid

References
References	Tamura, Y., et al. 1998. J. Med. Chem. 41, 640.

Product Information
CAS number	193807-58-8
ATP Competitive	N
Form	White solid
Hill Formula	C₂₁H₁₉NO₄S
Chemical formula	C₂₁H₁₉NO₄S
Reversible	N
Structure formula Image
Quality Level	MQ100

Applications

Biological Information
Primary Target	MMP-2, MMP-9
Primary Target IC<sub>50</sub>	310 nM and 240 nM against MMP-2 and MMP-9
Purity	≥95% by HPLC

Physicochemical Information
Cell permeable	N

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Ambient Temperature Only
Toxicity	Standard Handling
Storage	-20°C
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Packaging Information
Packaged under inert gas	Packaged under inert gas

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
444241-5MGCN	07790788056384

Documentation

MMP-2/MMP-9 Inhibitor I - CAS 193807-58-8 - Calbiochem MSDS

职位
物料安全数据表 (MSDS)

MMP-2/MMP-9 Inhibitor I - CAS 193807-58-8 - Calbiochem 分析证书

标题	批号
444241	输入批号

参考

参考信息概述
Tamura, Y., et al. 1998. J. Med. Chem. 41, 640.

数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	01-April-2011 RFH
Synonyms	(2R)-2-[(4-Biphenylylsulfonyl)amino]-3-phenylpropionic Acid
Description	A potent inhibitor of MMP-2 (gelatinase A; IC₅₀ = 310 nM) and MMP-9 (gelatinase B; IC₅₀ = 240 nM).
Form	White solid
Intert gas (Yes/No)	Packaged under inert gas
CAS number	193807-58-8
Chemical formula	C₂₁H₁₉NO₄S
Structure formula
Purity	≥95% by HPLC
Solubility	DMSO (200 mg/ml)
Storage	-20°C
Do Not Freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Toxicity	Standard Handling
References	Tamura, Y., et al. 1998. J. Med. Chem. 41, 640.

种类

Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Proteases Inhibitors > Matrix Metalloproteinase (MMP) Inhibitors

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