数量	产品目录编号	订购说明	数量 / 包装	公开价
			96-Well Plate

数量	产品目录编号	订购说明	数量 / 包装	公开价
	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

HCYTPAB-96SK MilliporeMILLIPLEX^® Human Cytokine Panel A + B 96-Plex Combo Pack

Simultaneously analyze 48 cytokine, chemokine, and growth factor biomarkers with each Bead-Based Multiplex Assay using the Luminex technology, in human serum, plasma and cell culture samples.

Recommended Products

概述

Replacement Information

Description
Catalogue Number	HCYTPAB-96SK
Trade Name	MILLIPLEX
Description	MILLIPLEX^® Human Cytokine Panel A + B 96-Plex Combo Pack
Overview	MILLIPLEX^® offers the broadest selection of analytes across a wide range of disease states and species. Once the analytes of interest have been identified, you can rely on the quality that we build into each kit to produce results you can trust. In addition to the assay characteristics listed in the protocol, other performance criteria evaluated during the verification process include: cross-reactivity, dilution linearity, kit stability, and sample behavior (e.g. detectability and stability). Each MILLIPLEX^® panel and kit includes: • Quality controls (QCs) to qualify assay performance • Comparison of standard (calibrator) and QC lots to a reference lot to ensure lot-to-lot consistency • Optimized serum matrix to mimic native analyte environment in serum and plasma samples • Detection antibody cocktails designed to yield consistent analyte profiles within panel In addition each panel and kit meets stringent manufacturing criteria to ensure batch-to-batch reproducibility. The MILLIPLEX^® Human Cytokine/Chemokine/Growth Factor Panel A thus enables you to focus on the therapeutic potential of cytokines and the modulation of cytokine expression. Coupled with the Luminex^® xMAP^® platform in a magnetic bead format, you receive the advantage of ideal speed and sensitivity, allowing quantitative multiplex detection of dozens of analytes simultaneously, which can dramatically improve productivity.
Background Information	Cytokines, chemokines, and growth factors are key mediators of immune system functions capable of signaling through autocrine, paracrine, and endocrine mechanisms. Their pleiotropic immunomodulatory properties allow these biomolecules to react to diverse stimuli and regulate the immune response, either by promoting or inhibiting inflammation. Growing research continues to highlight the role of the immune system in every facet of human health and disease.

References

Product Information
Detection method	Luminex xMAP
Configuration	Premixed
Precision, %	Intra-Assay: <15% Inter-assay: <20%
Panel Type	MAGNETIC Cytokines/Chemokines

Applications
Application	Simultaneously analyze 48 cytokine, chemokine, and growth factor biomarkers with each Bead-Based Multiplex Assay using the Luminex technology, in human serum, plasma and cell culture samples.
Key Applications	Multiplexing
Application Notes	• This is an overnight or two-hour incubation assay. • Each assay requires 25 µL of neat plasma or serum, or 25 μL cell culture supernatant per well. • Two kits are included and are intended to be run separately.

Biological Information
Species Reactivity	Human
Analytes Available	EGF Eotaxin G-CSF GM-CSF IFNα2 IFNγ IL-1α IL-1β IL-1ra IL-2 IL-3 IL-4 IL-5 IL-6 IL-7 IL-8 IL-12 (p40) IL-12(p70) IL-13 IL-15 IL-17A IL-17E/IL-25 IL-17F IL-18 IL-22 IP-10/CXCL10 MCP-1 M-CSF MIG MIP-1α MIP-1β PDGF-AA PDGF-AB/BB RANTES TNFα TNFβ VEGF-A 6Ckine sCD137 sFas sFasL APRIL/TNFSF13 BAFF/Blys BCA-1 CTACK ENA-78 Eotaxin-2 Eotaxin-3 Granzyme A Granzyme B HMGB1 I-309 IFNβ IL-16 IL-20 IL-21 IL-23 IL-28A IL-29 IL-31 IL-33 I-TAC LIF MCP-2 MCP-4 MIP-1d MIP-3α Perforin SCF SDF-1 TARC TPO TRAIL TSLP sCD40L FGF-2 Flt-3 Fractalkine MDC (CCL22) IL-11 IL-24 IL-34 MIP-3β MPIF-1/CCL23 GROα IL-9 IL-10 MCP-3 TGFα CCL28 CXCL16 IL-35 GCP2 IFNω Lymphotactin
Cross Reactivity	There was no or negligible cross-reactivity observed between the antibodies for any single analyte and any of the other analytes in this panel, except IL-12 (p40). IL-12 (p40) exhibited a cross-reactivity of approximately 8% with IL-12 (p70). This is not unexpected since the p40 subunit is a constituent of IL-12 (p70).
Accuracy	81%-106%

Physicochemical Information
Sensitivity	Refer to kit protocol for sensitivities for individual cytokines, chemokines and growth factors.
Standard Curve Range	MIP-1β: 0.38 - 6,000 pg/mL IL-2, IL-4, IL-5, IL-6, IL-7, IL-8, IL-9, IL-18, MDC: 0.64 - 10,000 pg/mL FLT-3L: 0.96 - 15,000 pg/mL GROα, IFNγ, IL-3, IL-17A, RANTES, TGFα: 1.3 - 20,000 pg/mL IL-1β, IL-1RA, TNFβ: 1.6 - 25,000 pg/mL GM-CSF, IL-10, IP-10, VEGF-A: 2.6 - 40,000 pg/mL EGF, Eotaxin, IL-12 (p70), IL-15, MCP-1, MIP-1α: 3 - 50,000 pg/mL G-CSF, IL-1α: 4.8 - 75,000 pg/mL IL-12 (p40), IL-13, MIG, TNFα: 6.4 - 100,000 pg/mL IFNα2, MCP-3: 8 - 125,000 pg/mL PDGF-AB/BB: 9.6 - 150,000 pg/mL sCD40L, IL-22, PDGF-AA: 13 - 200,000 pg/mL IL-27: 16 - 250,000 pg/mL FGF-2: 26 - 400,000 pg/mL Fractalkine, IL-17F: 32 - 500,000 pg/mL IL-17E/IL-25, M-CSF: 40 - 625,000 pg/mL 6CKine: 37-150,000 pg/mL BCA-1, MCP-4: 1.7-7,000 pg/mL sFas: 0.3-1,100 ng/mL sFasL, IL-33: 20-80,000 pg/mL CTACK: 3.7-15,000 pg/mL CXCL16, Eotaxin-3, IL-21, IL-28A: 4.9-20,000 pg/mL ENA-78: 3.1-12,500 pg/mL GCP-2: 0.9-3,500 pg/mL sCD137, APRIL, Granzyme A, Eotaxin-2, IFNβ, IFNω, IL-11, IL-31, LIF, TRAIL: 2.4-10,000 pg/mL BAFF: 13-55,000 pg/mL IL-16, IL-34, MIP-1δ: 10-40,000 pg/mL CCL28: 61-250,000 pg/mL IL-35, SCF, SDF-1, TPO: 12-50,000 pg/mL HMGB1: 134-550,000 pg/mL I-309: 1.5-6,000 pg/mL Granzyme B: 1.8-7,500 pg/mL IL-23, IL-24: 24-100,000 pg/mL IL-20: 15-60,000 pg/mL IL-29: 6.1-25,000 pg/mL Lymphotactin: 7.3-30,000 pg/mL MCP-2: 0.2-1,000 pg/mL MIP-3α: 0.6-2,500 pg/mL I-TAC, MIP-3β: 1.2-5,000 pg/mL MPIF-1: 1.0-4,000 pg/mL TARC: 0.8-3,250 pg/mL TSLP: 0.5-2,000 pg/mL Perforin: 18-75,000 pg/mL

Physicochemical Information

Sensitivity

Refer to kit protocol for sensitivities for individual cytokines, chemokines and growth factors.

Standard Curve Range

MIP-1β: 0.38 - 6,000 pg/mL
IL-2, IL-4, IL-5, IL-6, IL-7, IL-8, IL-9, IL-18, MDC: 0.64 - 10,000 pg/mL
FLT-3L: 0.96 - 15,000 pg/mL
GROα, IFNγ, IL-3, IL-17A, RANTES, TGFα: 1.3 - 20,000 pg/mL
IL-1β, IL-1RA, TNFβ: 1.6 - 25,000 pg/mL
GM-CSF, IL-10, IP-10, VEGF-A: 2.6 - 40,000 pg/mL
EGF, Eotaxin, IL-12 (p70), IL-15, MCP-1, MIP-1α: 3 - 50,000 pg/mL
G-CSF, IL-1α: 4.8 - 75,000 pg/mL
IL-12 (p40), IL-13, MIG, TNFα: 6.4 - 100,000 pg/mL
IFNα2, MCP-3: 8 - 125,000 pg/mL
PDGF-AB/BB: 9.6 - 150,000 pg/mL
sCD40L, IL-22, PDGF-AA: 13 - 200,000 pg/mL
IL-27: 16 - 250,000 pg/mL
FGF-2: 26 - 400,000 pg/mL
Fractalkine, IL-17F: 32 - 500,000 pg/mL
IL-17E/IL-25, M-CSF: 40 - 625,000 pg/mL
6CKine: 37-150,000 pg/mL
BCA-1, MCP-4: 1.7-7,000 pg/mL
sFas: 0.3-1,100 ng/mL
sFasL, IL-33: 20-80,000 pg/mL
CTACK: 3.7-15,000 pg/mL
CXCL16, Eotaxin-3, IL-21, IL-28A: 4.9-20,000 pg/mL
ENA-78: 3.1-12,500 pg/mL
GCP-2: 0.9-3,500 pg/mL
sCD137, APRIL, Granzyme A, Eotaxin-2, IFNβ, IFNω, IL-11, IL-31, LIF, TRAIL: 2.4-10,000 pg/mL
BAFF: 13-55,000 pg/mL
IL-16, IL-34, MIP-1δ: 10-40,000 pg/mL
CCL28: 61-250,000 pg/mL
IL-35, SCF, SDF-1, TPO: 12-50,000 pg/mL
HMGB1: 134-550,000 pg/mL
I-309: 1.5-6,000 pg/mL
Granzyme B: 1.8-7,500 pg/mL
IL-23, IL-24: 24-100,000 pg/mL
IL-20: 15-60,000 pg/mL
IL-29: 6.1-25,000 pg/mL
Lymphotactin: 7.3-30,000 pg/mL
MCP-2: 0.2-1,000 pg/mL
MIP-3α: 0.6-2,500 pg/mL
I-TAC, MIP-3β: 1.2-5,000 pg/mL
MPIF-1: 1.0-4,000 pg/mL
TARC: 0.8-3,250 pg/mL
TSLP: 0.5-2,000 pg/mL
Perforin: 18-75,000 pg/mL

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements
Usage Statement	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information
Storage Conditions	Recommended storage for kit components is 2 - 8°C.

Packaging Information
Material Size	96-well plate
Material Package	2 kits to be run separately

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
HCYTPAB-96SK	04065270020079

Documentation

Protocols

Title
Protocol- HCYTB-60K\|HCYTB-60K-PX38\|HCYTB-60K-PXBK38\|HCYTB-60K-PX48\|HCYTB-60K-PXBK48\|HCYTPB-76K\|HCYTPAB-76SK\|HCYTPB-96K\|HCYTPAB-96SK

MILLIPLEX^® Human Cytokine Panel A + B 96-Plex Combo Pack MSDS

职位
物料安全数据表 (MSDS)

用户指南

标题
User Guide-MILLIPLEX® Human Cytokine/Chemokine/Growth Factor Panel B Magnetic Bead Panel

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HCYTPAB-96SK MilliporeMILLIPLEX^® Human Cytokine Panel A + B 96-Plex Combo Pack

Simultaneously analyze 48 cytokine, chemokine, and growth factor biomarkers with each Bead-Based Multiplex Assay using the Luminex technology, in human serum, plasma and cell culture samples.

Recommended Products

概述

Documentation

Protocols

MILLIPLEX^® Human Cytokine Panel A + B 96-Plex Combo Pack MSDS

用户指南

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Simultaneously analyze 48 cytokine, chemokine, and growth factor biomarkers with each Bead-Based Multiplex Assay using the Luminex technology, in human serum, plasma and cell culture samples.

Recommended Products

Protocols

MILLIPLEX® Human Cytokine Panel A + B 96-Plex Combo Pack MSDS

用户指南

最近查看的内容

MILLIPLEX^® Human Cytokine Panel A + B 96-Plex Combo Pack MSDS