475848 Sigma-AldrichMIF Antagonist V, p425 - CAS 259444 - Calbiochem
The MIF Antagonist V, p425, also referenced under CAS 2610-05-1, controls the biological activity of MIF. This small molecule/inhibitor is primarily used for Cell Structure applications.
More>> The MIF Antagonist V, p425, also referenced under CAS 2610-05-1, controls the biological activity of MIF. This small molecule/inhibitor is primarily used for Cell Structure applications. Less<<MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
同义词: Sodium 6,6ʹ-(1E,1ʹE)-(3,3ʹ-dimethoxybiphenyl-4,4ʹ-diyl)bis(diazene-2,1-diyl)bis(4-amino-5-hydroxynaphthalene-1,3-disulfonate)
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概述
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重要规格表
| CAS # | Empirical Formula |
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| 2610-05-1 | C₃₄H₂₄N₆Na₄O₁₆S₄ |
价格及供货情况
| 产品目录编号 | 库存情况 | 包装 | 数量 / 包装 | 价格 | 数量 | |
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| 475848-2GMCN |
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玻璃瓶 | 2 gm |
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| Description | |
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| Overview | A symmetrical bis-(amino, hydroxynaphthalenedisulfonate) compound that antagonizes macrophage migration inhibitory factor against receptor binding (IC50 = 810 nM against hMIF and CD74 interaction) and is more potent than ISO-1 (Cat. No. 475837) in suppressing MIF-induced cytokines and MMP-3 productions in human fibroblasts cultures (IC50 = ≤0.7 µM vs >5 µM). Unlike MIF Antagonists I-IV, p425 targets an area at the interface of two MIF trimers, distal to the active site. |
| Catalogue Number | 475848 |
| Brand Family | Calbiochem® |
| Synonyms | Sodium 6,6ʹ-(1E,1ʹE)-(3,3ʹ-dimethoxybiphenyl-4,4ʹ-diyl)bis(diazene-2,1-diyl)bis(4-amino-5-hydroxynaphthalene-1,3-disulfonate) |
| References | |
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| References | Bai, F., et al. 2012. J. Biol. Chem. 287, 30653. |
| Product Information | |
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| CAS number | 2610-05-1 |
| Form | Blue solid |
| Hill Formula | C₃₄H₂₄N₆Na₄O₁₆S₄ |
| Hygroscopic | Hygroscopic |
| Reversible | Y |
| Structure formula Image | |
| Quality Level | MQ100 |
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| Biological Information | |
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| Primary Target | MIF |
| Purity | ≥95% by HPLC |
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| Safety Information according to GHS |
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| Packaging Information | |
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| Packaged under inert gas | Packaged under inert gas |
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| Specifications |
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| Global Trade Item Number | |
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| 产品目录编号 | GTIN |
| 475848-2GMCN | 04055977185034 |
Documentation
MIF Antagonist V, p425 - CAS 259444 - Calbiochem MSDS
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MIF Antagonist V, p425 - CAS 259444 - Calbiochem 分析证书
| 标题 | 批号 |
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| 475848 |
参考
| 参考信息概述 |
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| Bai, F., et al. 2012. J. Biol. Chem. 287, 30653. |
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Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
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