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			96-Well Plate

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	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

437725 Sigma-AldrichLipoxin A₄, 15-epi - CAS 171030-11-8 - Calbiochem

Lipoxin A₄, 15-epi, CAS 171030-11-8, is an epimeric lipoxin A4 (Cat. No. 437720) analog that is more potent and metabolically stable than LXA4.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书
参考
Data Sheet

同义词: LXA₄-15-epi, 15(R)-LXA₄, Aspirin-triggered LXA₄, (5S,6R,15R)-5,6,15-Trihydroxy-7,9,13-trans-11-cis-eicosatetraenoic acid

Recommended Products

概述

Replacement Information

重要规格表

CAS #	Empirical Formula
171030-11-8	C₂₀H₃₂O₅

价格及供货情况

产品目录编号	库存情况	包装	数量 / 包装	价格	数量
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Description
Overview	A epimeric lipoxin A₄ (Cat. No. 437720) analog that is more potent and metabolically stable than LXA₄. Exhibits anti-inflammatory properties and serves as a "stop signal" to excessive leukocyte trafficking/infiltration. Blocks TNF-α-induced IL-8 release in human enterocyte. It is also an important modulator of the many pharmacological actions caused by aspirin.
Overview	Caution! Product contains volatile liquid. Keep product cold at all times.
Catalogue Number	437725
Brand Family	Calbiochem®
Synonyms	LXA₄-15-epi, 15(R)-LXA₄, Aspirin-triggered LXA₄, (5S,6R,15R)-5,6,15-Trihydroxy-7,9,13-trans-11-cis-eicosatetraenoic acid

References
References	Wallace, J.L., and Fiorucci, S. 2003. Trends Pharmacol. Sci. 24, 323. Filep, J.G., et al. 2002. Adv. Exp. Med. Biol. 507, 223. Titos, E., et al. 1999. Am. J. Physiol. 277, C870. Gronert, K., et al. 1998. J. Exp. Med. 187, 1285. Maddox, J.F., et al. 1997. J. Biol. Chem. 272, 6972. Claria, J., et al. 1996. Mol. Med. 2, 583. Claria, J., and Serhan, C.N. 1995. Proc. Natl. Acad. Sci. USA 92, 9475. Serhan, C.N., et al. 1995. Biochemistry 34, 14609.

References

Wallace, J.L., and Fiorucci, S. 2003. Trends Pharmacol. Sci. 24, 323.
Filep, J.G., et al. 2002. Adv. Exp. Med. Biol. 507, 223.
Titos, E., et al. 1999. Am. J. Physiol. 277, C870.
Gronert, K., et al. 1998. J. Exp. Med. 187, 1285.
Maddox, J.F., et al. 1997. J. Biol. Chem. 272, 6972.
Claria, J., et al. 1996. Mol. Med. 2, 583.
Claria, J., and Serhan, C.N. 1995. Proc. Natl. Acad. Sci. USA 92, 9475.
Serhan, C.N., et al. 1995. Biochemistry 34, 14609.

Product Information
CAS number	171030-11-8
ATP Competitive	N
Form	Liquid
Formulation	In Ethanol.
Hill Formula	C₂₀H₃₂O₅
Chemical formula	C₂₀H₃₂O₅
Hygroscopic	Hygroscopic
Reversible	N
Structure formula Image
Quality Level	MQ100

Applications

Biological Information
Primary Target	Exhibits anti-inflammatory properties
Purity	≥98% by HPLC

Physicochemical Information
Cell permeable	N

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Dry Ice Only
Toxicity	Flammable
Hazardous Materials Attention:	Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Storage	≤ -70°C
Protect from Light	Protect from light
Hygroscopic	Hygroscopic
Do not freeze	Ok to freeze
Special Instructions	Following initial thaw aliquot and freeze (-70°C).

Packaging Information
Packaged under inert gas	Packaged under inert gas

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
437725-25UGCN	04055977186895

Documentation

Lipoxin A₄, 15-epi - CAS 171030-11-8 - Calbiochem MSDS

职位
物料安全数据表 (MSDS)

Lipoxin A₄, 15-epi - CAS 171030-11-8 - Calbiochem 分析证书

标题	批号
437725	输入批号

参考

参考信息概述
Wallace, J.L., and Fiorucci, S. 2003. Trends Pharmacol. Sci. 24, 323. Filep, J.G., et al. 2002. Adv. Exp. Med. Biol. 507, 223. Titos, E., et al. 1999. Am. J. Physiol. 277, C870. Gronert, K., et al. 1998. J. Exp. Med. 187, 1285. Maddox, J.F., et al. 1997. J. Biol. Chem. 272, 6972. Claria, J., et al. 1996. Mol. Med. 2, 583. Claria, J., and Serhan, C.N. 1995. Proc. Natl. Acad. Sci. USA 92, 9475. Serhan, C.N., et al. 1995. Biochemistry 34, 14609.

参考信息概述

数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	06-August-2008 RFH
Synonyms	LXA₄-15-epi, 15(R)-LXA₄, Aspirin-triggered LXA₄, (5S,6R,15R)-5,6,15-Trihydroxy-7,9,13-trans-11-cis-eicosatetraenoic acid
Description	An epimeric lipoxin A₄ (Cat. No. 437720) analog that is more potent and metabolically stable than LXA₄. Exhibits anti-inflammatory properties and serves as a "stop signal" to excessive leukocyte trafficking/infiltration. Reported to block TNF-α-induced IL-8 release in human enterocytes. Also reported to be an important modulator of the pharmacological actions of aspirin. Caution! Product contains volatile liquid; keep cold at all times.
Form	Liquid
Formulation	In Ethanol.
Intert gas (Yes/No)	Packaged under inert gas
CAS number	171030-11-8
Chemical formula	C₂₀H₃₂O₅
Structure formula
Purity	≥98% by HPLC
Storage	Protect from light ≤ -70°C Hygroscopic
Do Not Freeze	Ok to freeze
Special Instructions	Following initial thaw aliquot and freeze (-70°C).
Toxicity	Flammable
References	Wallace, J.L., and Fiorucci, S. 2003. Trends Pharmacol. Sci. 24, 323. Filep, J.G., et al. 2002. Adv. Exp. Med. Biol. 507, 223. Titos, E., et al. 1999. Am. J. Physiol. 277, C870. Gronert, K., et al. 1998. J. Exp. Med. 187, 1285. Maddox, J.F., et al. 1997. J. Biol. Chem. 272, 6972. Claria, J., et al. 1996. Mol. Med. 2, 583. Claria, J., and Serhan, C.N. 1995. Proc. Natl. Acad. Sci. USA 92, 9475. Serhan, C.N., et al. 1995. Biochemistry 34, 14609.

种类

Life Science Research > Inhibitors and Biochemicals > Biochemicals > Lipids > Leukotrienes, Prostaglandins and Other Eicosanoids

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