428021 Sigma-AldrichLatrunculin A, Latrunculia magnifica - CAS 76343-93-6 - Calbiochem
Latrunculin A, CAS 76343-93-6, is a cell-permeable marine toxin that disrupts microfilament organization in cultured cells by the formation of a 1:1 complex with monomeric G-actin (KD = 200 nM).
More>> Latrunculin A, CAS 76343-93-6, is a cell-permeable marine toxin that disrupts microfilament organization in cultured cells by the formation of a 1:1 complex with monomeric G-actin (KD = 200 nM). Less<<MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
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概述
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重要规格表
CAS # | Empirical Formula |
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76343-93-6 | C₂₂H₃₁NO₅S |
价格及供货情况
产品目录编号 | 库存情况 | 包装 | 数量 / 包装 | 价格 | 数量 | |
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428021-100UGCN |
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塑胶安瓿;塑胶针药瓶 | 100 μg |
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Description | |
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Overview | A cell-permeable marine toxin that disrupts microfilament organization in cultured cells by the formation of a 1:1 complex with monomeric G-actin (Kd = 200 nM). Also a potent inhibitor of microfilament-mediated processes in sperm, eggs, and embryos. A 1 mM (50 µg/119 µl) solution of Latrunculin A, Latrunculia magnifica Cat. No. 428026 in DMSO is also available. |
Catalogue Number | 428021 |
Brand Family | Calbiochem® |
Product Information | |
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CAS number | 76343-93-6 |
ATP Competitive | N |
Form | White solid |
Hill Formula | C₂₂H₃₁NO₅S |
Chemical formula | C₂₂H₃₁NO₅S |
Reversible | N |
Structure formula Image | |
Quality Level | MQ100 |
Applications |
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Biological Information | |
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Primary Target | G-actin |
Primary Target IC<sub>50</sub> | Kd = 200 nM in formation of a 1:1 complex with monomeric G-actin |
Purity | ≥95% by HPLC |
Physicochemical Information | |
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Cell permeable | Y |
Dimensions |
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Materials Information |
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Toxicological Information |
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Safety Information according to GHS |
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Safety Information | |
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R Phrase | R: 20/21/22 Harmful by inhalation, in contact with skin and if swallowed. |
S Phrase | S: 36 Wear suitable protective clothing. |
Product Usage Statements |
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Packaging Information | |
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Packaged under inert gas | Packaged under inert gas |
Transport Information |
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Supplemental Information |
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Specifications |
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Global Trade Item Number | |
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产品目录编号 | GTIN |
428021-100UGCN | 07790788050214 |
Documentation
Latrunculin A, Latrunculia magnifica - CAS 76343-93-6 - Calbiochem MSDS
职位 |
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Latrunculin A, Latrunculia magnifica - CAS 76343-93-6 - Calbiochem 分析证书
标题 | 批号 |
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428021 |
参考
参考信息概述 |
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Ayscough, K.R., et al. 1997. J. Cell Biol. 137, 399. Spector, I., et al. 1989. Cell Motil. Cytoskeleton 13, 127. Coue, M., et al. 1987. FEBS Lett. 213, 316. Schatten, G., et al. 1986. Exp. Cell Res. 166, 191. Spector, I., et al. 1983. Science 219, 493. |