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A potent agonist and assumed endogenous ligand of GPR55, shown to induce rapid phosphorylation of p38 mitogen-activated protein kinase (MAPK) and its downstream activating transcription factor 2 (ATF2) in both GPR55-transfected HEK293 cells, and in IM-9 lymphoblastoid cells naturally expressing GPR55 at 1uM, while having no effect on vector-transfected cells. In addition, shown to enhance serum induced cell migration in MCF-7 cells over expressing GPR55.
L-α-lysophosphatidylinositol Sodium Salt, Soy - CAS 796963-91-2 - Calbiochem 分析证书
标题
批号
440153
参考
参考信息概述
Oka, S., et al. 2010. J Biochem.147, 671. Oka, S., et al. 2007. Biochem. Biophys. Res. Commun.362, 928.
数据表
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
A potent agonist and assumed endogenous ligand of GPR55, shown to induce rapid phosphorylation of p38 mitogen-activated protein kinase (MAPK) and its downstream activating transcription factor 2 (ATF2) in both GPR55-transfected HEK293 cells, and in IM-9 lymphoblastoid cells naturally expressing GPR55 at 1 µM, while having no effect on vector-transfected cells. In addition, shown to enhance serum induced cell migration in MCF-7 cells over expressing GPR55.
Form
White powder
Intert gas (Yes/No)
Packaged under inert gas
CAS number
796963-91-2
Chemical formula
C₂₅H₄₈NaO₁₂P
Structure formula
Purity
>99% by HPLC
Solubility
DMSO
Storage
Protect from moisture
Protect from light
-20°C
Hygroscopic
Do Not Freeze
Ok to freeze
Special Instructions
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity
Standard Handling
References
Oka, S., et al. 2010. J Biochem.147, 671. Oka, S., et al. 2007. Biochem. Biophys. Res. Commun.362, 928.
