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420134 JNK Inhibitor VII, TAT-TI-JIP153-163, Cell-Permeable - Calbiochem

概述

Replacement Information

重要规格表

Empirical Formula
C₁₂₅H₂₂₀N₅₂O₂₇

价格及供货情况

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420134-2MGCN
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      Description
      OverviewThe non-permeant JNK inhibitor peptide TI-JIP153-163 (Cat. No. 420133) is made cell-permeable with an N-terminal TAT protein transduction domain sequence. Shown to offer neuroprotection in a rat ischemic brain injury model in in vivo.
      Catalogue Number420134
      Brand Family Calbiochem®
      SynonymsH₂N-YGRKKRRQRRR-RPKRPTTLNLF-NH₂, TAT₃₈₋₄₈ -Truncated Inhibitor based on JNK-Interacting Protein 1
      References
      ReferencesGuan, Q.H., et al. 2006. Neuroscience, 139, 609.
      Barr, R.K., et al. 2004. J. Biol. Chem. 279, 36327.
      Bogoyevitch, M.A., et al. 2003. Cell. Mol. Biol. Lett. 8, 550.
      Barr, R.K., et al. 2002. J. Biol. Chem. 277, 10987.
      Product Information
      ATP CompetitiveN
      FormLyophilized
      FormulationSupplied as a trifluoroacetate salt.
      Hill FormulaC₁₂₅H₂₂₀N₅₂O₂₇
      Chemical formulaC₁₂₅H₂₂₀N₅₂O₂₇
      Hygroscopic Hygroscopic
      ReversibleN
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetJNK
      Purity≥97% by HPLC
      Physicochemical Information
      Cell permeableY
      Peptide SequenceH-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Arg-Pro-Lys-Arg-Pro-Thr-Thr-Leu-Asn-Leu-Phe-NH₂
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      产品目录编号 GTIN
      420134-2MGCN 04055977187649

      Documentation

      JNK Inhibitor VII, TAT-TI-JIP153-163, Cell-Permeable - Calbiochem MSDS

      职位

      物料安全数据表 (MSDS) 

      JNK Inhibitor VII, TAT-TI-JIP153-163, Cell-Permeable - Calbiochem 分析证书

      标题批号
      420134

      参考

      参考信息概述
      Guan, Q.H., et al. 2006. Neuroscience, 139, 609.
      Barr, R.K., et al. 2004. J. Biol. Chem. 279, 36327.
      Bogoyevitch, M.A., et al. 2003. Cell. Mol. Biol. Lett. 8, 550.
      Barr, R.K., et al. 2002. J. Biol. Chem. 277, 10987.
      数据表

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision25-July-2008 RFH
      SynonymsH₂N-YGRKKRRQRRR-RPKRPTTLNLF-NH₂, TAT₃₈₋₄₈ -Truncated Inhibitor based on JNK-Interacting Protein 1
      DescriptionThe non-permeant JNK inhibitor peptide TI-JIP153-163 (Cat. No. 420133) is made cell-permeable with an N-terminal TAT protein transduction domain sequence. Shown to offer neuroprotection in a rat ischemic brain injury model in in vivo.
      FormLyophilized
      FormulationSupplied as a trifluoroacetate salt.
      Intert gas (Yes/No) Packaged under inert gas
      Chemical formulaC₁₂₅H₂₂₀N₅₂O₂₇
      Peptide SequenceH-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Arg-Pro-Lys-Arg-Pro-Thr-Thr-Leu-Asn-Leu-Phe-NH₂
      Purity≥97% by HPLC
      SolubilityDMSO (5 mg/ml) or H₂O (1 mg/ml)
      Storage Protect from light
      +2°C to +8°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Toxicity Standard Handling
      ReferencesGuan, Q.H., et al. 2006. Neuroscience, 139, 609.
      Barr, R.K., et al. 2004. J. Biol. Chem. 279, 36327.
      Bogoyevitch, M.A., et al. 2003. Cell. Mol. Biol. Lett. 8, 550.
      Barr, R.K., et al. 2002. J. Biol. Chem. 277, 10987.