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			96-Well Plate

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	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

407951 MilliporeIonomycin, Free Acid, Streptomyces conglobatus in Solution - CAS 56092-81-0 - Calbiochem

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书
参考
Data Sheet
Citations

Recommended Products

概述

Replacement Information

重要规格表

CAS #	Empirical Formula
56092-81-0	C₄₁H₇₂O₉

价格及供货情况

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Description
Catalogue Number	407951
Brand Family	Calbiochem®

References
References	Aagaard-Tillery, K.M., and Jelinek, D.F. 1995. J. Immunol. 155, 3297. Takei, N., and Endo, Y. 1994. Brain Res. 652, 65. Dupuy d’Angeac, A., et al. 1993. J. Cell Physiol. 154, 44. Lee, H.C. 1993. J. Biol. Chem. 268, 293. Kuznetsov, G., et al. 1992. J. Biol. Chem. 267, 3932. Toeplitz, B.K., et al. 1979. J. Am. Chem. Soc. 101, 3344. Liu, C.M., and Hermann, T.E. 1978. J. Biol. Chem. 253, 5892.

References

Aagaard-Tillery, K.M., and Jelinek, D.F. 1995. J. Immunol. 155, 3297.
Takei, N., and Endo, Y. 1994. Brain Res. 652, 65.
Dupuy d’Angeac, A., et al. 1993. J. Cell Physiol. 154, 44.
Lee, H.C. 1993. J. Biol. Chem. 268, 293.
Kuznetsov, G., et al. 1992. J. Biol. Chem. 267, 3932.
Toeplitz, B.K., et al. 1979. J. Am. Chem. Soc. 101, 3344.
Liu, C.M., and Hermann, T.E. 1978. J. Biol. Chem. 253, 5892.

Product Information
CAS number	56092-81-0
ATP Competitive	N
Form	Clear, colorless to slight yellow solution
Formulation	A 5 mM (1 mg/282 µl) solution of Ionomycin, Free Acid, Streptomyces conglobatus (Cat. No. 407950) in DMSO.
Hill Formula	C₄₁H₇₂O₉
Chemical formula	C₄₁H₇₂O₉
Hygroscopic	Hygroscopic
Reversible	N
Structure formula Image
Quality Level	MQ100

Applications

Biological Information
Primary Target	Mobile ion carrier for Ca2+.
Purity	≥90% by HPLC

Physicochemical Information
Cell permeable	Y

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Shipped with Blue Ice or with Dry Ice
Toxicity	Irritant
Storage	-20°C
Protect from Light	Protect from light
Hygroscopic	Hygroscopic
Do not freeze	Ok to freeze
Special Instructions	Following initial thaw, aliquot and freeze (-20°C).

Packaging Information
Packaged under inert gas	Packaged under inert gas

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
407951-1MGCN	04055977211580

Documentation

Ionomycin, Free Acid, Streptomyces conglobatus in Solution - CAS 56092-81-0 - Calbiochem MSDS

职位
物料安全数据表 (MSDS)

Ionomycin, Free Acid, Streptomyces conglobatus in Solution - CAS 56092-81-0 - Calbiochem 分析证书

标题	批号
407951	输入批号

参考

参考信息概述
Aagaard-Tillery, K.M., and Jelinek, D.F. 1995. J. Immunol. 155, 3297. Takei, N., and Endo, Y. 1994. Brain Res. 652, 65. Dupuy d’Angeac, A., et al. 1993. J. Cell Physiol. 154, 44. Lee, H.C. 1993. J. Biol. Chem. 268, 293. Kuznetsov, G., et al. 1992. J. Biol. Chem. 267, 3932. Toeplitz, B.K., et al. 1979. J. Am. Chem. Soc. 101, 3344. Liu, C.M., and Hermann, T.E. 1978. J. Biol. Chem. 253, 5892.

参考信息概述

引用

标题

Jonathan Rios-Doria, et al. (2004) Cleavage of b-catenin by calpain in prostate and mammary tumor cells. Cancer Research 64, 7237-7240.

数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	01-April-2011 RFH
Description	Highly specific for divalent cations (Ca²⁺ > Mg²⁺ >> Sr²⁺ = Ba²⁺). More effective than antibiotic A23187 as a mobile ion carrier for Ca²⁺. Complexes with Ca²⁺ between pH 7 and 9.5, causing significant absorption in the UV range; however, in contrast to A23187 (Cat. No. 100105), it is not fluorescent. Useful for studies of Ca²⁺ transport across biological membranes and measurement of cytoplasmic free Ca²⁺. Induces apoptotic neuronal degeneration in embryonic cortical neurons. Also induces cell cycle arrest in the G₁ interval of mature Burkitt lymphoma cell lines.
Form	Clear, colorless to slight yellow solution
Formulation	A 5 mM (1 mg/282 µl) solution of Ionomycin, Free Acid, Streptomyces conglobatus (Cat. No. 407950) in DMSO.
Intert gas (Yes/No)	Packaged under inert gas
CAS number	56092-81-0
Chemical formula	C₄₁H₇₂O₉
Structure formula
Purity	≥90% by HPLC
Storage	Protect from light -20°C Hygroscopic
Do Not Freeze	Ok to freeze
Special Instructions	Following initial thaw, aliquot and freeze (-20°C).
Toxicity	Irritant
References	Aagaard-Tillery, K.M., and Jelinek, D.F. 1995. J. Immunol. 155, 3297. Takei, N., and Endo, Y. 1994. Brain Res. 652, 65. Dupuy d’Angeac, A., et al. 1993. J. Cell Physiol. 154, 44. Lee, H.C. 1993. J. Biol. Chem. 268, 293. Kuznetsov, G., et al. 1992. J. Biol. Chem. 267, 3932. Toeplitz, B.K., et al. 1979. J. Am. Chem. Soc. 101, 3344. Liu, C.M., and Hermann, T.E. 1978. J. Biol. Chem. 253, 5892.
Citation	Jonathan Rios-Doria, et al. (2004) Cleavage of b-catenin by calpain in prostate and mammary tumor cells. Cancer Research 64, 7237-7240.

种类

Life Science Research > Inhibitors and Biochemicals > Biochemicals > Ionophores

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