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	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

584223 Sigma-AldrichInSolution™ Tetrahydrouridine - CAS 18771-50-1 - Calbiochem

Tetrahydrouridine is a potent competitive inhibitor of cytidine deaminase.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书
参考
Data Sheet

同义词: 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-hydroxytetrahydropyrimidin-2(1H)-one, dihydrate, THU, H4U

Primary Target: cytidine deaminase

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概述

Replacement Information

重要规格表

CAS #	Empirical Formula
18771-50-1	C₉H₁₆N₂O₆ • 2H₂O

价格及供货情况

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Description
Overview	A potent competitive inhibitor of cytidine deaminase. Used in combination with cytosine arabinoside (Ara-C) to assess the anti-leukemic activity and anti-tumor activity of Ara-C in in vitro studies. The solid form of this compound (Cat. No. 584222) is also available.
Catalogue Number	584223
Brand Family	Calbiochem®
Synonyms	1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-hydroxytetrahydropyrimidin-2(1H)-one, dihydrate, THU, H4U

References
References	Yusa, K., et al. 1995. Biochem. Biophys. Res. Commun. 206, 486. Bouffard, D.Y., et al. 1993. Biochem Pharmacol. 45, 1857. Laliberte, J., et al. 1992. Cancer Chemotherap. Pharmacol. 30, 7. Riva, C., et al. 1992. Chemotherapy 38, 358. Yusa, K., et al. 1992. J. Biol. Chem. 267, 16848. Hanze, A.R. 1967. J. Am. Chem. Soc. 89, 6720.

Product Information
CAS number	18771-50-1
Form	Liquid
Formulation	A 100 mM (25 mg/879 µL) solution of Tetrahydrouridine (Cat. No. 584222) in H₂O.
Hill Formula	C₉H₁₆N₂O₆ • 2H₂O
Reversible	Y
Structure formula Image
Quality Level	MQ100

Applications

Biological Information
Primary Target	cytidine deaminase
Purity	≥90% by TLC

Physicochemical Information
Cell permeable	Y

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Dry Ice Only
Toxicity	Standard Handling
Storage	≤ -70°C
Protect from Light	Protect from light
Avoid freeze/thaw	Avoid freeze/thaw
Do not freeze	Ok to freeze
Special Instructions	Following initial thaw, aliquot and freeze (-70°C). Aliquots are stable for up to 6 months at -70°C.

Packaging Information
Packaged under inert gas	Packaged under inert gas

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
584223-25MGCN	04055977264999

Documentation

InSolution™ Tetrahydrouridine - CAS 18771-50-1 - Calbiochem MSDS

职位
物料安全数据表 (MSDS)

InSolution™ Tetrahydrouridine - CAS 18771-50-1 - Calbiochem 分析证书

标题	批号
584223	输入批号

参考

参考信息概述
Yusa, K., et al. 1995. Biochem. Biophys. Res. Commun. 206, 486. Bouffard, D.Y., et al. 1993. Biochem Pharmacol. 45, 1857. Laliberte, J., et al. 1992. Cancer Chemotherap. Pharmacol. 30, 7. Riva, C., et al. 1992. Chemotherapy 38, 358. Yusa, K., et al. 1992. J. Biol. Chem. 267, 16848. Hanze, A.R. 1967. J. Am. Chem. Soc. 89, 6720.

数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	03-January-2019 JSW
Synonyms	1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-hydroxytetrahydropyrimidin-2(1H)-one, dihydrate, THU, H4U
Description	A potent competitive inhibitor of cytidine deaminase. Used in combination with cytosine arabinoside (Ara-C) to assess the anti-leukemic activity and anti-tumor activity of Ara-C in in vitro studies. The solid form of this compound (Cat. No. 584222) is also available.
Form	Liquid
Formulation	A 100 mM (25 mg/879 µL) solution of Tetrahydrouridine (Cat. No. 584222) in H₂O.
Intert gas (Yes/No)	Packaged under inert gas
CAS number	18771-50-1
Structure formula
Purity	≥90% by TLC
Storage	Protect from light Avoid freeze/thaw ≤ -70°C
Do Not Freeze	Ok to freeze
Special Instructions	Following initial thaw, aliquot and freeze (-70°C). Aliquots are stable for up to 6 months at -70°C.
Toxicity	Standard Handling
References	Yusa, K., et al. 1995. Biochem. Biophys. Res. Commun. 206, 486. Bouffard, D.Y., et al. 1993. Biochem Pharmacol. 45, 1857. Laliberte, J., et al. 1992. Cancer Chemotherap. Pharmacol. 30, 7. Riva, C., et al. 1992. Chemotherapy 38, 358. Yusa, K., et al. 1992. J. Biol. Chem. 267, 16848. Hanze, A.R. 1967. J. Am. Chem. Soc. 89, 6720.

种类

Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Other Inhibitors of Biological Interest

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