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	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

508225 Sigma-AldrichInSolution™ Tamoxifen, 4-Hydroxy-, (Z)- - CAS 68047-06-3 - Calbiochem

A 10 mM (2 mg/516 µL) sterile-filtered solution of (Z)-4-Hydroxytamoxifen in ethanol.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
参考
Data Sheet

同义词: (Z)-4-(1-(4-(Dimethylaminoethoxy)phenyl)-2-phenyl-1-butenyl)phenol, (Z)-4-(1-(4-(2-(Dimethylamino)ethoxy)phenyl)-2-phenylbut-1-enyl)phenol, (Z)-4-Hydroxytamoxifen, (Z)-4-OH-TAM, trans-4-Hydroxytamoxifen

Primary Target: Estrogen receptor

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概述

Replacement Information

重要规格表

CAS #	Empirical Formula
68047-06-3	C₂₆H₂₉NO₂

价格及供货情况

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Description
Catalogue Number	508225
Brand Family	Calbiochem®
Synonyms	(Z)-4-(1-(4-(Dimethylaminoethoxy)phenyl)-2-phenyl-1-butenyl)phenol, (Z)-4-(1-(4-(2-(Dimethylamino)ethoxy)phenyl)-2-phenylbut-1-enyl)phenol, (Z)-4-Hydroxytamoxifen, (Z)-4-OH-TAM, trans-4-Hydroxytamoxifen

References
References	Gundimeda, U., et al. 1996. J. Biol. Chem. 271, 13504. Ye, Q. and Bodell, W.J. 1996. Carcinogenesis 17, 1747. Laser, R., et al. 1985. Eur. J. Cancer Clin. Oncol. 21, 985. Jordan, V.C., et al. 1978. J. Toxicol. Environ. Health 4, 364.

Product Information
CAS number	68047-06-3
Form	Liquid
Formulation	A 10 mM (2 mg/516 µL) sterile-filtered solution of (Z)-4-Hydroxytamoxifen (Cat. No. 579002) in EtOH.
Hill Formula	C₂₆H₂₉NO₂
Chemical formula	C₂₆H₂₉NO₂
Hygroscopic	Hygroscopic
Reversible	Y
Structure formula Image
Quality Level	MQ100

Applications

Biological Information
Primary Target	Estrogen receptor
Purity	≥99% by HPLC

Physicochemical Information
Cell permeable	Y

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information
R Phrase	R: 11 Highly flammable.
S Phrase	S: 16-7 Keep away from sources of ignition - No Smoking. Keep container tightly closed.

Product Usage Statements

Storage and Shipping Information
Ship Code	Dry Ice Only
Toxicity	Harmful & Carcinogenic / Teratogenic
Hazardous Materials Attention:	Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Storage	≤ -70°C
Protect from Light	Protect from light
Hygroscopic	Hygroscopic
Avoid freeze/thaw	Avoid freeze/thaw
Do not freeze	Ok to freeze
Special Instructions	Following initial thaw, aliquot and freeze (-20°C). Aliquots are stable for up to 6 months at -20°C. Use only anhydrous, 200 proof ethanol for further dilutions.

Packaging Information
Packaged under inert gas	Packaged under inert gas

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
5.08225.0001	04055977261769

Documentation

InSolution™ Tamoxifen, 4-Hydroxy-, (Z)- - CAS 68047-06-3 - Calbiochem MSDS

职位
物料安全数据表 (MSDS)

参考

参考信息概述
Gundimeda, U., et al. 1996. J. Biol. Chem. 271, 13504. Ye, Q. and Bodell, W.J. 1996. Carcinogenesis 17, 1747. Laser, R., et al. 1985. Eur. J. Cancer Clin. Oncol. 21, 985. Jordan, V.C., et al. 1978. J. Toxicol. Environ. Health 4, 364.

数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	17-January-2014 JSW
Synonyms	(Z)-4-(1-(4-(Dimethylaminoethoxy)phenyl)-2-phenyl-1-butenyl)phenol, (Z)-4-(1-(4-(2-(Dimethylamino)ethoxy)phenyl)-2-phenylbut-1-enyl)phenol, (Z)-4-Hydroxytamoxifen, (Z)-4-OH-TAM, trans-4-Hydroxytamoxifen
Description	A cell-permeable, active metabolite of Tamoxifen (Cat. No. 579000) that acts as a potent inhibitor of PKC. It is more potent than the parent compound and inhibits PKC by modifying its catalytic domain.
Form	Liquid
Formulation	A 10 mM (2 mg/516 µL) sterile-filtered solution of (Z)-4-Hydroxytamoxifen (Cat. No. 579002) in EtOH.
Intert gas (Yes/No)	Packaged under inert gas
CAS number	68047-06-3
Chemical formula	C₂₆H₂₉NO₂
Structure formula
Purity	≥99% by HPLC
Storage	Protect from light Avoid freeze/thaw ≤ -70°C Hygroscopic
Do Not Freeze	Ok to freeze
Special Instructions	Following initial thaw, aliquot and freeze (-20°C). Aliquots are stable for up to 6 months at -20°C. Use only anhydrous, 200 proof ethanol for further dilutions.
Toxicity	Harmful & Carcinogenic / Teratogenic
References	Gundimeda, U., et al. 1996. J. Biol. Chem. 271, 13504. Ye, Q. and Bodell, W.J. 1996. Carcinogenesis 17, 1747. Laser, R., et al. 1985. Eur. J. Cancer Clin. Oncol. 21, 985. Jordan, V.C., et al. 1978. J. Toxicol. Environ. Health 4, 364.

种类

Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Protein Phosphorylation / Dephosphorylation > Protein Kinase C (PKC) Inhibitors

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