数量	产品目录编号	订购说明	数量 / 包装	公开价
			96-Well Plate

数量	产品目录编号	订购说明	数量 / 包装	公开价
	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

509612 Sigma-AldrichInSolution™ TAPI-2 - CAS 187034-31-7 - Calbiochem

A 10 mM (1 mg/241 µL) sterile-filtered solution of TAPI-2 in H₂O.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
参考
Data Sheet

Recommended Products

概述

Replacement Information

重要规格表

CAS #	Empirical Formula
187034-31-7	C₁₉H₃₇N₅O₅

价格及供货情况

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Description
Catalogue Number	509612
Brand Family	Calbiochem®

References
References	Bennett, T.A., et al. 2000. J. Immunol. 164, 4120. Fiorucci, S., et al. 1998. Aliment. Pharmacol. Ther. 12, 1139. Hooper, N.M., et al. 1997. Biochem. J. 321, 265. Parvathy, S., et al. 1997. Biochem. J. 327, 37. Arribas, J., et al. 1996. J. Biol. Chem. 271, 11376.

Product Information
CAS number	187034-31-7
Form	Liquid
Formulation	A 10 mM (1 mg/241 µL) sterile-filtered solution of TAPI-2 (Cat. No. 579052) in H₂O.
Hill Formula	C₁₉H₃₇N₅O₅
Chemical formula	C₁₉H₃₇N₅O₅
Quality Level	MQ100

Applications

Biological Information
Purity	≥97% by HPLC

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Dry Ice Only
Toxicity	Standard Handling
Storage	≤ -70°C
Protect from Light	Protect from light
Do not freeze	Ok to freeze
Special Instructions	Following initial thaw, aliquot and freeze (-20°C). Aliquots are stable for up to 3 months at -20°C.

Packaging Information
Packaged under inert gas	Packaged under inert gas

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
5.09612.0001	04055977240986

Documentation

InSolution™ TAPI-2 - CAS 187034-31-7 - Calbiochem MSDS

职位
物料安全数据表 (MSDS)

参考

参考信息概述
Bennett, T.A., et al. 2000. J. Immunol. 164, 4120. Fiorucci, S., et al. 1998. Aliment. Pharmacol. Ther. 12, 1139. Hooper, N.M., et al. 1997. Biochem. J. 321, 265. Parvathy, S., et al. 1997. Biochem. J. 327, 37. Arribas, J., et al. 1996. J. Biol. Chem. 271, 11376.

数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	18-April-2014 JSW
Description	A hydroxamate-based inhibitor of matrix metalloproteinases and TACE (TNF-α convertase; ADAM17). Inhibits the activation-dependent shedding of L-selectin from neutrophils, eosinophils, and lymphocytes as well as phenylarsine oxide (PAO)-induced shedding in neutrophils. Also blocks the shedding of several cell surface proteins such as pro-TGF-α, IL-6 receptor α-subunit, and β-amyloid precursor protein. Reported to inhibit TNF-α release and impart protection against aspirin-induced gastric mucosal injury. Acts as a weak inhibitor of angiotensin converting enzyme (IC₅₀ = 18 µM).
Form	Liquid
Formulation	A 10 mM (1 mg/241 µL) sterile-filtered solution of TAPI-2 (Cat. No. 579052) in H₂O.
Intert gas (Yes/No)	Packaged under inert gas
CAS number	187034-31-7
Chemical formula	C₁₉H₃₇N₅O₅
Purity	≥97% by HPLC
Storage	Protect from light ≤ -70°C
Do Not Freeze	Ok to freeze
Special Instructions	Following initial thaw, aliquot and freeze (-20°C). Aliquots are stable for up to 3 months at -20°C.
Toxicity	Standard Handling
References	Bennett, T.A., et al. 2000. J. Immunol. 164, 4120. Fiorucci, S., et al. 1998. Aliment. Pharmacol. Ther. 12, 1139. Hooper, N.M., et al. 1997. Biochem. J. 321, 265. Parvathy, S., et al. 1997. Biochem. J. 327, 37. Arribas, J., et al. 1996. J. Biol. Chem. 271, 11376.

种类

Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Proteases Inhibitors > Collagenase Inhibitors

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