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540223 Sigma-AldrichInSolution™ Purmorphamine - Calbiochem

InSolution™ Purmorphamine, CAS 483367-10-8, is a provided as a 50 mM solution in DMSO. Induces osteoblast differentiation of multipotent mesenchymal progenitor cells C3H10T1/2 & lineage-committed preosteoblasts MC3T3-E1.

InSolution™ Purmorphamine - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书
参考
Data Sheet

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概述

Replacement Information

重要规格表

Empirical Formula
C₃₁H₃₂N₆O₂

价格及供货情况

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Description
Catalogue Number	540223
Brand Family	Calbiochem®

References
References	Wu, X., et al. 2004. Chem. Biol. 11, 1229. Wu, X., et al. 2002. J. Am. Chem. Soc. 124, 14520.

Product Information
Form	Liquid
Formulation	A 50 mM (5 mg/192 µl) solution of Purmorphamine (Cat. No. 540220) in DMSO.
Hill Formula	C₃₁H₃₂N₆O₂
Chemical formula	C₃₁H₃₂N₆O₂
Hygroscopic	Hygroscopic
Structure formula Image
Quality Level	MQ100

Applications
Application	InSolution™ Purmorphamine, CAS 483367-10-8, is a provided as a 50 mM solution in DMSO. Induces osteoblast differentiation of multipotent mesenchymal progenitor cells C3H10T1/2 & lineage-committed preosteoblasts MC3T3-E1.

Biological Information
Purity	≥98% by HPLC

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information
R Phrase	R: 36/38 Irritating to eyes and skin.
S Phrase	S: 26-36-45 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing. In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).

Product Usage Statements

Storage and Shipping Information
Ship Code	Shipped with Blue Ice or with Dry Ice
Toxicity	Irritant
Storage	-20°C
Protect from Light	Protect from light
Hygroscopic	Hygroscopic
Do not freeze	Ok to freeze
Special Instructions	Following initial thaw, aliquot and freeze (-20°C).

Packaging Information
Packaged under inert gas	Packaged under inert gas

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
540223-5MGCN	04055977268782

Documentation

InSolution™ Purmorphamine - Calbiochem MSDS

职位
物料安全数据表 (MSDS)

InSolution™ Purmorphamine - Calbiochem 分析证书

标题	批号
540223	输入批号

参考

参考信息概述
Wu, X., et al. 2004. Chem. Biol. 11, 1229. Wu, X., et al. 2002. J. Am. Chem. Soc. 124, 14520.

数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	26-August-2008 JSW
Description	A cell-permeable purine compound that induces osteoblast differentiation in C3H10T1/2 multipotent mesenchymal progenitor cells (EC₅₀ = 1 µM) and in MC3T3-E1 lineage-committed preosteoblasts. Also shown to induce transdifferentiation in pre-adipocytes and myoblasts. Its effects are reported to be synergistic with bone morphogenetic protein-4 (BMP-4). Reported to induce osteogenesis by activation of the Hedgehog signaling pathway.
Form	Liquid
Formulation	A 50 mM (5 mg/192 µl) solution of Purmorphamine (Cat. No. 540220) in DMSO.
Intert gas (Yes/No)	Packaged under inert gas
Chemical formula	C₃₁H₃₂N₆O₂
Structure formula
Purity	≥98% by HPLC
Storage	Protect from light -20°C Hygroscopic
Do Not Freeze	Ok to freeze
Special Instructions	Following initial thaw, aliquot and freeze (-20°C).
Toxicity	Irritant
References	Wu, X., et al. 2004. Chem. Biol. 11, 1229. Wu, X., et al. 2002. J. Am. Chem. Soc. 124, 14520.

种类

Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Activators > Other Activators/Agonists

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